A noticeable part of the microbiome literature, especially that working with low-biomass samples, is plagued by reagent contamination. Here we describe visual, statistical, methodical and ecological techniques to facilitate recognition of signals that represent contamination.
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Acknowledgements
The work was supported by the Medical Research Council (UK; G1100221) and the National Institute for Health Research (NIHR) Cambridge Comprehensive Biomedical Research Centre (Women’s Health theme).
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de Goffau, M.C., Lager, S., Salter, S.J. et al. Recognizing the reagent microbiome. Nat Microbiol 3, 851–853 (2018). https://doi.org/10.1038/s41564-018-0202-y
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DOI: https://doi.org/10.1038/s41564-018-0202-y
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