ANTIVIRALS

Longing for HIV protection

Antibodies that potently neutralize highly diverse HIV-1 variants offer great potential for therapy and prevention. Passive administration of HIV-specific neutralizing antibodies genetically modified to have a long serum half-life has now been shown to confer long-lasting protection from infection in the rhesus macaque model.

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Fig. 1: Goals for the effective implementation of a passive bNAb immunization.

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Correspondence to Guido Silvestri.

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Zanoni, M., Palesch, D. & Silvestri, G. Longing for HIV protection. Nat Microbiol 3, 648–649 (2018). https://doi.org/10.1038/s41564-018-0169-8

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