Feature | Published:

Material aid for vaccines

Nature Materialsvolume 17pages472473 (2018) | Download Citation

Darrell Irvine provides an overview of the recent advances in materials science that have enabled the use of innovative natural and synthetic compounds in vaccine development capable of regulating the potency and safety of new vaccines progressing towards the clinic.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.


  1. 1.

    Wu, T. Y.-H. et al. Sci. Transl. Med 6, 263ra160 (2014).

  2. 2.

    Lynn, G. M. et al. Nat. Biotechnol. 33, 1201–1210 (2015).

  3. 3.

    Kuai, R., Ochyl, L. J., Bahjat, K. S., Schwendeman, A. & Moon, J. J. Nat. Mater. 16, 489–496 (2017).

  4. 4.

    Liu, H. et al. Nature 507, 519–252 (2014).

  5. 5.

    Ali, O. A., Huebsch, N., Cao, L., Dranoff, G. & Mooney, D. J. Nat. Mater. 8, 151–158 (2009).

  6. 6.

    Kranz, L. M. et al. Nature 534, 396–401 (2016).

  7. 7.

    Bahl, K. et al. Mol. Ther. 25, 1316–1327 (2017).

  8. 8.

    Alberer, M. et al. Lancet 390, 1511–1520 (2017).

  9. 9.

    Brito, L. A. et al. Mol. Ther. 22, 2118–2129 (2014).

  10. 10.

    Maldonado, R. A. et al. Proc. Natl Acad. Sci. USA 112, E156–E165 (2015).

Download references

Author information


  1. Department of Biological Engineering, Department of Materials Science and Engineering, and Koch Institute for Integrative Cancer Research, MIT, Cambridge, MA, USA

    • Darrell Irvine
  2. Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA

    • Darrell Irvine
  3. Howard Hughes Medical Institute, Chevy Chase, MD, USA

    • Darrell Irvine


  1. Search for Darrell Irvine in:

Corresponding author

Correspondence to Darrell Irvine.

About this article

Publication history




Newsletter Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing