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African genomes hold the key to accurate genetic risk prediction

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Fig. 1: A growing number of African genome resources are capturing genetic diversity across Africa, which is key to improving the power and equitability of PRS across global populations.

References

  1. Campbell, M. C. & Tishkoff, S. A. Curr. Biol. 20, R166–R173 (2010).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Fatumo, S. et al. Nat. Med. 28, 243–250 (2022).

    Article  CAS  PubMed  Google Scholar 

  3. Kullo, I. J. et al. Nat. Rev. Genet. 23, 524–532 (2022).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Kamiza, A. B. et al. Nat. Med. 28, 1163–1166 (2022).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Chikowore, T. et al. Diabetes Care 45, 717–723 (2022).

    Article  PubMed  PubMed Central  Google Scholar 

  6. Bentley, A. R., Callier, S. L. & Rotimi, C. N. Med. 5, 5 (2020).

    Google Scholar 

  7. Barroso, I. Diabetologia 64, 2653–2664 (2021).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Owolabi, M. O. et al. Int. J. Epidemiol. 48, 366–367g (2019).

    Article  PubMed  Google Scholar 

  9. Fatumo, S. et al. Nat. Genet. 54, 531–536 (2022).

    Article  CAS  PubMed  Google Scholar 

  10. Fatumo, S. et al. Cell Genomics 2, 100209 (2022).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

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Correspondence to Segun Fatumo.

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Fatumo, S., Inouye, M. African genomes hold the key to accurate genetic risk prediction. Nat Hum Behav 7, 295–296 (2023). https://doi.org/10.1038/s41562-023-01549-1

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