Cancer (r)evolution

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Cancer evolution is central to poor outcomes of cancer therapies, enabling tumour progression and the acquisition of drug resistance. Joint efforts of evolutionary biologists, oncologists and cancer researchers are necessary to understand the principles of cancer evolution and to derive therapeutic strategies that can control it.

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References

  1. 1.

    Gerlinger, M. et al. Annu. Rev. Genet. 48, 215–236 (2014).

    CAS  Article  PubMed  Google Scholar 

  2. 2.

    Gerlinger, M. et al. Nat. Genet. 46, 225–233 (2014).

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  3. 3.

    Bettegowda, C. et al. Sci. Transl. Med. 6, 224ra224 (2014).

    Article  Google Scholar 

  4. 4.

    Gundem, G. et al. Nature 520, 353–357 (2015).

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  5. 5.

    Prasad, V. Nature 537, S63 (2016).

    CAS  Article  PubMed  Google Scholar 

  6. 6.

    Matsushita, H. et al. Nature 482, 400–404 (2012).

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  7. 7.

    Siravegna, G. et al. Nat. Med. 21, 795–801 (2015).

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  8. 8.

    Gao, R. et al. Nat. Genet. 48, 1119–1130 (2016).

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  9. 9.

    Jamal-Hanjani, M. et al. PLoS Biol. 12, e1001906 (2014).

    Article  PubMed  PubMed Central  Google Scholar 

  10. 10.

    Barber, L. J., Davies, M. N. & Gerlinger, M. Curr. Opin. Genet. Dev. 30, 1–6 (2015).

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  11. 11.

    Williams, M. J., Werner, B., Barnes, C. P., Graham, T. A. & Sottoriva, A. Nat. Genet. 48, 238–244 (2016).

    CAS  Article  PubMed  PubMed Central  Google Scholar 

  12. 12.

    Lipinski, K. A. et al. Trends Cancer 2, 49–63 (2016).

    Article  PubMed  PubMed Central  Google Scholar 

  13. 13.

    Enriquez-Navas, P. M. et al. Sci. Transl. Med. 8, 327ra324 (2016).

    Article  Google Scholar 

  14. 14.

    Harris, R. S. Breast Cancer Res. 17, 8 (2015).

    Article  PubMed  PubMed Central  Google Scholar 

  15. 15.

    Drake, C. G., Lipson, E. J. & Brahmer, J. R. Nat. Rev. Clin. Oncol. 11, 24–37 (2014).

    CAS  Article  PubMed  Google Scholar 

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Correspondence to Marco Gerlinger.

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von Loga, K., Gerlinger, M. Cancer (r)evolution. Nat Ecol Evol 1, 1051–1052 (2017). https://doi.org/10.1038/s41559-017-0252-1

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