Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Research Briefing
  • Published:

Serial rotation electron diffraction for rapid phase analysis to accelerate materials development

Serial rotation electron diffraction (SerialRED) enables rapid and reliable phase analysis and structure determination of complex polycrystalline materials that cannot be routinely characterized using X-ray diffraction. Five zeolite phases were identified in a single synthesis product by automated screening of hundreds of crystals, demonstrating the power of SerialRED for materials development.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Fig. 1: Exploration of complex polycrystalline zeolite products using serial rotation electron diffraction (SerialRED).

References

  1. McCusker, L. & Baerlocher, C. Electron crystallography as a complement to X-ray powder diffraction techniques. Z. Kristallogr. 228, 1–10 (2013). This paper reports the shortcomings of powder XRD in phase and structural analysis and how electron crystallography can complement it.

    Article  CAS  Google Scholar 

  2. Baerlocher, C. et al. Structure of the polycrystalline zeolite catalyst IM-5 solved by enhanced charge flipping. Science 315, 1113–1116 (2007). This paper discusses the challenge of determining the structure of zeolites using powder XRD when the structures are complex.

    Article  CAS  PubMed  Google Scholar 

  3. Moliner, M., Román-Leshkov, Y. & Corma, A. Machine learning applied to zeolite synthesis: the missing link for realizing high-throughput discovery. Acc. Chem. Res. 52, 2971–2980 (2019). A review article that presents the high-throughput synthesis of zeolites and how machine learning can be integrated with high-throughput synthesis.

    Article  CAS  PubMed  Google Scholar 

  4. Gemmi, M. et al. 3D electron diffraction: the nanocrystallography revolution. ACS Cent. Sci. 5, 1315–1329 (2019). A review article that presents 3D ED methods and their applications in structure characterization of nanometre- and submicrometre-sized crystals.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Wang, B., Zou, X. & Smeets, S. Automated serial rotation electron diffraction combined with cluster analysis: an efficient multi-crystal workflow for structure determination. IUCrJ 6, 854–867 (2019). The original report of SerialRED, providing details of the method.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Additional information

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

This is a summary of: Luo, Y. et al. High-throughput phase elucidation of polycrystalline materials using serial rotation electron diffraction. Nat. Chem. https://doi.org/10.1038/s41557-022-01131-8 (2023).

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Serial rotation electron diffraction for rapid phase analysis to accelerate materials development. Nat. Chem. 15, 456–457 (2023). https://doi.org/10.1038/s41557-023-01172-7

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41557-023-01172-7

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing