The origin and evolution of translational machinery — which produces a specific peptide from an RNA sequence — is a major unsolved puzzle in prebiotic chemistry. Now, the coupling of amino acids directed by RNA templates in the absence of a ribosome provides clues on how this protein synthesis process might have started.
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Zheng, Y.Y., Sheng, J. The origin of translation. Nat. Chem. 13, 725–726 (2021). https://doi.org/10.1038/s41557-021-00760-9
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DOI: https://doi.org/10.1038/s41557-021-00760-9