Harnessing the unique catalytic properties of enzymes for abiotic reactions is a prized goal that has inspired a variety of approaches in enzyme design and engineering. Now, the transfer hydrogenation of ketones with silanes has been reported, catalysed by a native carbonic anhydrase.
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References
Knowles, J. R. Nature 350, 121–124 (1991).
Jiang, L. et al. Science 319, 1387–1391 (2008).
Röthlisberger, D. et al. Nature 453, 190–195 (2008).
Schwizer, F. et al. Chem. Rev. 118, 142–231 (2018).
Key, H. M., Dydio, P., Clark, D. S. & Hartwig, J. F. Nature 534, 534–537 (2016).
Kan, S. B. J., Lewis, R. D., Chen, K. & Arnold, F. H. Science 354, 1048–1051 (2016).
Ji, P., Park, J., Gu, Y., Clark, D. S. & Hartwig, J. F. Nat. Chem. https://doi.org/10.1038/s41557-020-00633-7 (2021).
Schilter, D., Camara, J. M., Huynh, M. T., Hammes-Schiffer, S. & Rauchfuss, T. B. Chem. Rev. 116, 8693–8749 (2016).
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Senn, H.M. Hydride surprise. Nat. Chem. 13, 297–299 (2021). https://doi.org/10.1038/s41557-021-00670-w
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DOI: https://doi.org/10.1038/s41557-021-00670-w
