Identifying chromatin modifications and their interactomes is imperative to understand how chromatin functions and is regulated. Now, two new studies report on chemical tools that enable characterization of the biological interactions within native chromatin.
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The authors declare no competing interests.
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Zhang, Y., Kutateladze, T.G. Exploring epigenetics with chemical tools. Nat. Chem. 12, 506–508 (2020). https://doi.org/10.1038/s41557-020-0471-y