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DYNAMIC COVALENT CHEMISTRY

SNAr stands corrected

Dynamic covalent chemistry combines the error-correcting behaviour of supramolecular chemistry with the robustness of covalent bonding, but relies on a somewhat limited set of reactions. Now, the classic nucleophilic aromatic substitution (SNAr) reaction has been shown to be reversible and self-correcting.

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References

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Correspondence to Wei Zhang.

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Fig. 1: Dynamic, self-correcting SNAr reaction.
Fig. 2: Macrocycle and polymer synthesized through SNAr.