Review Article | Open | Published:

Facilitators and barriers to physical activity following pulmonary rehabilitation in COPD: a systematic review of qualitative studies

npj Primary Care Respiratory Medicinevolume 28, Article number: 19 (2018) | Download Citation

Abstract

Pulmonary rehabilitation has short-term benefits on dyspnea, exercise capacity and quality of life in COPD, but evidence suggests these do not always translate to increased daily physical activity on a patient level. This is attributed to a limited understanding of the determinants of physical activity maintenance following pulmonary rehabilitation. This systematic review of qualitative research was conducted to understand COPD patients’ perceived facilitators and barriers to physical activity following pulmonary rehabilitation. Electronic databases of published data, non-published data, and trial registers were searched to identify qualitative studies (interviews, focus groups) reporting the facilitators and barriers to physical activity following pulmonary rehabilitation for people with COPD. Thematic synthesis of qualitative data was adopted involving line-by-line coding of the findings of the included studies, development of descriptive themes, and generation of analytical themes. Fourteen studies including 167 COPD patients met the inclusion criteria. Seven sub-themes were identified as influential to physical activity following pulmonary rehabilitation. These included: intentions, self-efficacy, feedback of capabilities and improvements, relationship with health care professionals, peer interaction, opportunities following pulmonary rehabilitation and routine. These encapsulated the facilitators and barriers to physical activity following pulmonary rehabilitation and were identified as sub-themes within the three analytical themes, which were beliefs, social support, and the environment. The findings highlight the challenge of promoting physical activity following pulmonary rehabilitation in COPD and provide complementary evidence to aid evaluations of interventions already attempted in this area, but also adds insight into future development of interventions targeting physical activity maintenance in COPD.

Introduction

Chronic obstructive pulmonary disease (COPD) is a common and preventable condition, characterised by persistent respiratory symptoms and airflow limitation that is caused by significant exposure to noxious particles or gases.1 COPD is treatable, with the aim to manage symptoms and minimise disease progression; however, there is no cure. People with COPD have significantly lower levels of daily physical activity (PA) compared with age-matched healthy individuals,2,3,4,5,6,7 an avoidance of PA often related to exertional dyspnea which leads to increasing inactivity, muscle weakness and reduced exercise capacity. Physical inactivity predicts poor prognosis across the course of the disease,8,9 including reduced quality of life and increased risk of hospitalisation10,11,12,13 and mortality.14 As such, the importance of PA in COPD management is recognised, and there has been wide interest in strategies to promote and support PA.1

Pulmonary rehabilitation (PR) is defined as “a comprehensive intervention based on a thorough patient assessment followed by patient-tailored therapies that include, but are not limited to, exercise training, education, and behaviour change, designed to improve the physical and psychological condition of people with chronic respiratory disease and to promote the long-term adherence to health-enhancing behaviour”.15 The key benefits of PR include clinically important improvements in dyspnoea, physical capacity, and quality of life.16 Exercise capacity has been regarded as key to modifying PA in COPD.17 However, increased exercise capacity following PR does not directly translate to an increase in daily PA15,18 and long-term behaviour change in COPD. It has been suggested that longer-lasting PR programmes are more effective than shorter programmes in increasing PA levels but the effect remains controversial.19 Others who have aimed to increase PA through exercise training have only identified modest, short-term increases in PA.18,20 Based on current available evidence it appears exercise training alone is not enough to maintain PA in COPD.15,20,21

Evidence from a recent systematic review and meta-analysis identified only individualised or pedometer-based counselling added to multidisciplinary PR produce changes that exceed the established minimal clinical important difference in daily steps for COPD.20 The minimal efficacy of interventions surrounding PA and behaviour change following PR has been attributed to the limited understanding concerning the determinants of PA on a patient level in COPD.14 It has been acknowledged that it is likely not to be a “one size fits all” regarding strategies to maintain short-term benefits of PR,22 and widespread individual differences of PA in response to PR have been proposed.17,23,24,25

PA is a complex behaviour,14,15,17,18,20,21,24,25 but thus far syntheses of the research surrounding PA following PR is predominantly based on randomised controlled trials using quantitative methods alone.18,20,21 These methods do not capture individuals’ insights on how and why interventions did, or did not promote PA. The use of qualitative methods enables researchers to gain a comprehensive understanding of the effectiveness of health interventions, providing complementary data to quantitative findings in randomised controlled trials. Systematic review of qualitative studies have provided evidence toward understanding the COPD patients’ subjective view of the impact of PR,24 and the barriers and enablers to participation in structured PA (i.e., exercise/PR programmes).25 Such evidence does not address the factors which influence the maintenance of PA and long-term behaviour change following PR, where the focus shifts to self-management of PA. Specific factors are proposed to be involved in maintenance of behaviour, different from those involved in behaviour initiation;26 however, these factors have not been explored in this specific population.

There is a need for a better insight into the patient subjective experience of PA following completion of PR to inform future practice and policies surrounding support of long-term adherence to health-enhancing behaviour in COPD. The aim of this systematic review was to therefore provide a comprehensive synthesis of the patient reported facilitators and barriers of PA following completion of PR, among individuals with COPD.

Results

Study selection

Following removal of duplicates, searching identified 2392 records for eligibility assessment, of which 2340 were excluded based on title and abstract (Fig. 1). Full text screening of the remaining records resulted in 18 records that were eligible for the review. A full list of excluded studies, together with reasons for exclusion, can be found in the Supplementary File. However, only 14 studies were included within the synthesis (n = 12 published articles; n = 2 theses). In two cases, records referred to the same study27,28,29,30 and the remaining studies31,32 (n = 2) were presented only as conference abstracts. These were identified as relevant to the research question of this review, but not eligible for inclusion within the synthesis of the results due to lack of availability of participant quotations.31,32 Authors of these studies were contacted for more information; however, there was no response from authors.

Fig. 1
Fig. 1

PRISMA flow chart representing the study screening process

Study characteristics

Twelve studies were of a qualitative study design only, and two studies were of a mixed-method design27,33 (Table 1). Studies were conducted in Canada,30,33,34 Norway,27,35,36 The Netherlands,37 England,38,39,40,41 USA,42,43 and Sweden44 between 1998 and 2017. All studies collected data using either semi-structured interviews,33,34,35,36,37,41,42,44 open-ended interviews,43 or focus groups.27,30,38,39,40 The type of analysis ranged from thematic analysis,27,30,34,35,39 template analysis,40 qualitative content analysis;37,44 analysis methods informed by grounded theory,38,41,42 methods informed by phenomenology,43 and one reported that their analysis adhered to “established guidelines”.33

Table 1 Characteristics of included studies

Overall, there were a total of 167 individuals diagnosed COPD across the studies (male = 92, female = 75). All participants had previously completed PR but the treatment varied on setting and duration. The duration of the PR ranged from 4–12 weeks and individuals attended either inpatient27,30,33,34,43 and outpatient PR venues35,37,38,40,41,42 or setting was not reported.36,39,44 Most individuals were not involved in PA maintenance interventions;33,34,35,36,37,39,40,41,42,43,44 however, some were involved in post-rehabilitation programmes, such as a 6-month community exercise maintenance programme,30 a 2-year tele-rehabilitation intervention,27 and approximately half of individuals within Hogg’s et al.38 study had received input regarding ongoing exercise programmes post-rehabilitation.38 The context of data collection after completion of PR also varied across studies. The data collection typically occurred at either the individuals’ home,33,36,41,43 the rehabilitation centre,27,34,38 or a combination of both35,37,42,44 and data collection settings were not reported in some studies.30,39,40 All but two of the studies collected data just once following PR. One study conducted two semi-structured interviews35 and the other conducted three focus groups.27 Data collection took place between 1–2 weeks and 42 months following completion of PR.

Critical appraisal

Critical appraisal of the studies was conducted by two reviewers (Table 2). All studies were interpreted as having a clearly focused research question or hypothesis, as having an appropriate research design, appropriate justification of sampling strategy, well-described method of data collection, an explicit discussion of ethical issues and a consistent approach to reporting the conclusions (within the abstract and discussion). For each criterion, most studies were interpreted as good quality, with the exception of conflicts of interest and sponsorships, which were reported in six studies.27,30,33,37,40,44 In four studies it was unclear how well the researchers knew the participants,30,34,35,42 and in two studies no description of the relationship between participant and researcher was reported.39,44 In one study, the analytical method was not found to be clearly justified.37 The credibility of one study was unclear, due to minimal quotations to support themes.35 In two studies there was a lack of primary data provided within the text to support the deducted themes and subthemes from the study.33,39 In one study, the author did not identify limitations.43

Table 2 Critical appraisal of the included studies

Data synthesis

During the synthesis of the data from the 14 studies included in this review, 7 sub-themes were identified as influential to PA following PR, which were organised into 3 analytical themes, including beliefs, social support, and environment. The theme “beliefs” has three sub-themes, including intentions, self-efficacy, and feedback of capabilities and improvements. The theme “social support” has two sub-themes, including relationship to health care professionals and peer interaction and the final theme “environment” also has two sub-themes, including opportunities following PR and routine (Fig. 2). Facilitators and barriers to PA within these analytical themes are presented within Table 3, alongside a selection of participant quotes from included studies to reflect these themes. A line of argument, depicting the key analytical themes and sub-themes are reported.

Fig. 2
Fig. 2

Concept map to illustrate the analytical themes and sub-themes relating to physical activity maintenance following pulmonary rehabilitation in COPD

Table 3 Analytical themes and sub-themes with reference to quotations within primary studies

Theme: beliefs

Thoughts surrounding the importance of PA, previous experiences prior to PR, recognition of improvements following PR, and confidence influence individuals’ intentions and motivation toward maintenance of PA following PR.

Sub-theme: intentions

Many individuals held the belief that PA was enjoyable and important for their physical and psychological well-being.27,35,37,42,43 Individuals’ beliefs toward PA often manifested into intentions to be more physically active.27,35,37,42,43 These beliefs were often influenced by individuals’ lifestyles prior to COPD diagnosis. For example, regular engagement in PA prior to COPD diagnosis facilitated positive intentions toward maintaining PA following PR.37,43 Information and education on PA was also identified as a facilitator to PA following PR, as it increased individuals’ understanding of the health benefits associated with PA.35,36,37,38,40,42,44

Intentions to be more physically active did not always translate into behaviour change. For example, in one study, individuals repeatedly indicated positive intentions toward PA following PR;43 however, they were labelled as non-exercise compliant, highlighting an intention-behaviour gap in PA.

Sub-theme: self-efficacy

Self-efficacy was a common theme throughout the data, referring to individuals’ beliefs in their ability to engage in PA. A barrier to PA maintenance was negative beliefs surrounding PA and health.36,38,40 These negative beliefs often stemmed from individuals’ previous experiences of PA that negatively affected their confidence and perceived capability of engaging in PA following PR. For example, individuals reported PA as too hard and that they were too restricted by symptoms such as breathlessness.38 Exacerbations and symptoms often led to psychological distress, for example, individuals reported feeling overwhelmed, saddened, and frustrated by their restrictions due to COPD,27,30,35,36,38,39,40,43 and these experiences negatively influenced individuals’ confidence to be active. Breathlessness and anxiety were repeatedly reported throughout the studies,35,36,38,43 and this anxiety represented a barrier to PA after PR when individuals were attempting to maintain PA at home or by themselves, especially when individuals felt socially isolated.35,43 Avoidance was a strategy developed to manage anxiety associated with breathlessness27,38,43 and individuals did not want to draw attention to themselves by exercising outside of the house.27 However, confidence to apply stress and breathing management techniques was often reported a facilitator to maintaining PA after PR.33,35,36,38,41,42 These skills were often learnt during PR, and were associated with feelings of increased self-efficacy and a sense of empowerment,27,41 and the newfound confidence also coincided with a more positive outlook on life.33

Sub-theme: feedback of capabilities and improvements

Feedback refers to monitoring and providing informative or evaluative information on the performance of PA behaviour.45 When individuals noticed their personal improvements, or recognised their capabilities,42 they were often more engaged or motivated by the outcomes, and felt empowered to maintain PA.27,30,37,38,41,42,43,44

This motivation was facilitated by long-term feedback from health professionals, for example, in a maintenance tele-rehabilitation study27 individuals reported that they had improved throughout the course, and felt a sense of accomplishment when discussing their progress, reporting that an upward feeling was important in motivating them to be active.27 Those who had noticed improvements in health wanted these benefits to be maintained, and reported that they wanted the exercise classes to continue.38 Positive feedback therefore promoted beliefs of improvement and encouraged individuals to stay active following PR. However, not recognising improvements was perceived as a barrier to PA maintenance, as individuals became unmotivated as they believed that the exercises were not worthwhile or helpful.27,43

Theme: social support

Other people played a significant role in individuals’ journeys following PR. The perception of feeling cared for, valued, and assisted within the home and the community were important, in addition to relating to others who are in similar situations.

Sub-theme: relationship with health care professionals

Individuals’ relationships with others had a large impact on their outlook and PA behaviour following PR, which extended beyond gaining feedback about their condition. Support from health care professionals was commonly reported as being important for individuals, whereby their authority instilled a sense of trust, and individuals felt safe and comforted by their presence after PR.27,30,34,35,37,38,42,43,44 Individuals were less fearful of being overwhelmed by their symptoms, were comforted by the opportunity to ask questions, and were encouraged by their interest in their personal health.34 A barrier to PA was the lack of maintained support from health care professionals, and individuals reported feeling unmotivated,27,34,38,43 for example, by a lack of encouragement, incentive, and uncertainty regarding transferring these exercises to a different environment, for example, to their home.38

Sub-theme: peer interaction

Interaction with peers was commonly reported as beneficial and it was considered a facilitator to the maintenance of PA, as it made PA more enjoyable and helped individuals conquer feelings of loneliness.27,30,34,35,37,38,39,40,43,44 The opportunity to discuss symptoms and compare notes with others in similar situations also helped reduce distress associated with symptoms. However, individuals reported having a sense of loneliness that was difficult to manage following PR,30,39,40 and a lack of peer interaction following PR was considered a barrier to PA.35,38,43

Individuals appreciated the ease of connecting with peers, even when in different counties.27 Throughout the studies, interest was expressed in the maintenance of interaction with peers with COPD after PR,35,38,43 but was also expressed in socialising with individuals with mixed conditions and other members of the community.30 Despite this, peer interaction was also recognised as a barrier to PA, as it elicited fear in individuals as others’ conditions were an unwanted reminder of the progressive nature of COPD.35,39,43 This response motivated individuals to avoid peers in attempt to deny the illness and return to normality.39

Theme: environment

Individuals’ surroundings influenced their opportunities to engage in PA following PR. In addition, individuals’ physical and social environment influenced their experiences and approach to maintaining a PA routine and successfully establishing habits following PR.

Sub-theme: opportunities to engage in PA following PR

Individuals often expressed the importance of structured and unstructured PA sessions after PR,34,38,39 in particular they would like access to PA maintenance.34,35 However, unclear information regarding maintenance sessions did not allow for individuals to consider alternative ways to be active, and was considered a barrier to PA.40 Barriers to attendance in maintenance sessions also involved issues surrounding cost and proximity30 and restrictions imposed by family and work responsibilities.44 There was mixed views on home exercises, with some individuals reported positively to them,27 whereas others did not feel like they would be helpful,38 reflecting individual differences in preferences of PA. Walking and cycling37 were considered enjoyable activities, as well as simply being outside to enjoy the scenery.43 Individual differences regarding their preferred PA meant that having various opportunities to engage in a variety of activities was therefore considered a facilitator to PA, whereas restricted choice was considered a barrier to PA.

Sub-theme: routine

Ongoing contact with health care professionals and peers through maintenance groups also provided a sense of structure following PR and the expectation and pressure to conform to pre-set times and activities was appreciated and regarded as a facilitator to maintaining PA.27 However, without access to ongoing structured PA sessions, individuals largely reported that a barrier to maintaining PA was falling back into old habits.35,36,39,43 Routine was considered an important facilitator by individuals throughout the studies.35,38,42,44 However, this routine was influenced by the individuals’ home life. For example, families’ understanding of COPD and their recognition of the importance of PA was identified as a facilitator to PA as they were able to provide support and encouragement,37 whereas attention sometimes added too much pressure to individuals dealing with COPD.27,43 For example, individuals did not appreciate their family telling them to exercise.43 Social isolation due to restricted access to structured PA groups, lack of motivation,38 as well as simply forgetting to be active43 were also all reasons why individuals fell back into their previous routines. In addition, establishing a successful routine was considered a long process which required patience,36 placing emphasis on the challenge faced by many individuals to avoid falling back into old habits established prior to PR.27,35,40,42

Discussion

Summary of the findings

The purpose of this review was to identify the patient reported facilitators and barriers of PA following PR. The analytical themes developed were beliefs, social support, and environment that encapsulated the identified patient reported facilitators and barriers of PA following PA. Key facilitators identified within this review were the perception of continued support from health care professionals, continued peer interaction, the sense of accomplishment gained through self-monitoring and feedback, as well as opportunities to access PA maintenance groups following PR that enabled individuals to form routines and establish habits. Key barriers to PA were symptoms that evoked anxiety and fear, for example, breathlessness upon exertion, restricted access to social support and structured maintenance sessions following PR, and lack of positive feedback regarding health which led to individuals being less likely to establish routines incorporating PA, and were more likely to return to previous habits formed prior to PR.

Strengths and limitations of this review

Extensive searches for existing and ongoing systematic reviews suggest that there are no other systematic reviews to synthesise qualitative studies of COPD patients’ experiences of PA following PR. This systematic review followed a pre-specified protocol, conducting a comprehensive search strategy that yielded 14 studies. Language, date, and publication restrictions were not imposed in the search strategy, unlike previous qualitative systematic reviews in relevant areas, whereby inclusion criteria was either restricted to articles published in English25,46 or a selection of languages24 and included only peer-reviewed articles.24,25,46 Unpublished data proved valuable in this review, with a large amount of original qualitative data that provided clear insight into patients’ perspectives regarding PA following PR. We therefore consider inclusion of unpublished evidence to be a key strength of this review and suggest systematic reviews of qualitative studies that do not adopt this approach are at risk of publication bias and excluding data relevant to their research question. The resulting context within the included studies was diverse in terms of individuals’ PR settings, PA experiences following PR, and the cultural setting within each country, meaning that it was possible to achieve a higher level of abstraction in the synthesis.47 Two records retrieved in our search strategy were conference abstracts,31,32 and based on the available information were deemed to meet the inclusion criteria. It may be considered a limitation that the data from these studies are not included in our synthesis; however, as findings largely reflected existing themes we feel access to the full studies is unlikely to change the conclusions drawn in this review.

Our approach to data (thematic) synthesis were in line with established methodology for systematic reviews of qualitative evidence,48 an interpretative approach which enables a summary of the descriptive themes from the primary studies, with a subsequent production of analytical themes through applying a higher-level theoretical framework to answer the research question. This approach was beneficial, as transparency between the developed themes within this review and the text from the primary studies was maintained. It has previously been suggested that qualitative synthesis such as meta-ethnography can de-contextualise the findings from the primary studies.49,50 However, efforts to preserve context, in line with previous methods in thematic synthesis,48 were taken to consistently refer to primary studies to check for contextual factors that could affect transferability. Additionally, by adoption of key principles of systematic reviews (extracting and tabulating study characteristics), facilitators and barriers reported in included studies can be considered alongside their specific clinical and methodological characteristics.

Like quantitative research, there are no standardised criteria for assessing the quality of all qualitative research.51 This systematic review yielded studies with varied designs, methodological and analytical approaches, meaning that a key challenge was assessing the quality of research. We adopted an approach of appraising study quality by assessment of study conduct using a previously used critical appraisal tool.52 In accordance with approaches in systematic reviews of quantitative evidence, and with limited evidence to suggest that quality of reporting is associated with the credibility and transferability of the findings in qualitative studies,53 we did not feel there was sufficient justification for exclusion or weighting of study data according to quality. For each criterion within our chosen critical appraisal tool,52 the majority of the studies were critically appraised favourably; however, the limitations in some of the included studies should be considered, for example, credibility was often jeopardised by the small amount of qualitative data provided throughout the studies and it was not possible to conclude whether selected quotes were biased toward researchers pre-existing views regarding their research question.

Comparison to previous reviews

No previous systematic review has synthesised qualitative data regarding facilitators and barriers to PA following PR. Meta-analyses of randomised controlled trials have provided limited success in demonstrating efficacy of interventions to improve PA in COPD, as effects are typically modest and short term.18,20 However, current proposals of the likely greater impact of longer duration PR programmes on modification of PA19 would support a key theme presented in our review, namely, that ongoing support from both health care professionals and peer interaction was a facilitator to PA maintenance. The importance of social support has previously been reported in systematic reviews researching individuals’ participation in PR24,25 and facilitators and barriers to PA in other lung conditions.46 Feeling supported by family throughout PR has been identified as a facilitator to PA during PR,24 but the results from this study suggest that family, friends, partners, and peers interaction are also important in the maintenance of PA.

During PR, it has previously been suggested that environmental and personal factors, in addition to social factors, have been recognised as influential to PA in patients with COPD.25 Environmental factors such as transportation and options regarding the type and intensity of PA were also considered influential factors to PA maintenance, as were personal factors associated with identity, for example, previous experiences with PA and previous lifestyles which affected individuals’ PA beliefs. In this review, a larger emphasis was placed on access to information regarding opportunities to engage in PA following PR, likely due to the responsibility of PA maintenance being shifted from health care professionals to patients after completing PR. Establishing a healthier routine is often reported to be a key benefit during PR;24 however, the findings from this review identified both the importance and difficulty of maintaining these PA routines and forming habits following PR. Interestingly, the length of the PR programme has previously been recognised as a barrier to PA,25 with less patients being likely to attend longer programmes; however, the findings in this review suggest that a barrier to PA maintenance is the loss of structure and contact with other people.

Unlike previous findings of key barriers to PR,25 smoking status was not identified as a barrier to PA maintenance in this systematic review. It may be argued that a greater proportion of COPD patients included in the present review (i.e., who completed PR) were less likely to be smokers who are associated with poorer completion rates in PR and hence have other important personal factors. Our findings suggest that COPD patients often reflect on their health. Positive feedback regarding PA and health was recognised as a facilitator to PA maintenance, whereas some became unmotivated if they did not recognise any improvements in their condition. This suggests that self-efficacy is an influential factor in PA motivation, complementing findings of previous systematic reviews that reported goal achievement as a facilitator to PA during PR, and the benefits of adding pedometer-based counselling to multidisciplinary PR.20,25

Implications for research and practice

This systematic review furthers our understanding regarding the key factors that influence PA maintenance following PR in COPD and it provides evidence for health care professionals to consider when discussing individualised self-management plans on discharge from PR. Likewise, given that a typical pathway following PR includes referral of patients back to their primary care providers, this review provides important information for clinicians and healthcare professionals in these settings to consider when delivering long-term COPD management. Our findings provide complementary evidence to aid evaluations of PA interventions already attempted in this area,18,19,20,21 but also adds further insight into future development of interventions targeting PA maintenance in COPD. Based on the available evidence, further trials in this area should consider intervention functions which promote maintenance of social support from the health care professionals, maintenance of peer interaction following PR, promote a range of opportunities after PR to cater various PA preferences, and optimise individuals’ opportunities to recognise improvements in their health through techniques such as feedback and counselling to boost self-efficacy. This can be achieved by exploiting the use of wearable devices such as pedometers or through the use of information and communication technologies (tablet computers, smartphone applications, websites).

This systematic review further highlights the large variance of individual differences within the population who complete PR, supporting the statement that there is not a “one size fits all” approach to achieving lasting behaviour change following PR.22 This should be considered when tailoring interventions to individual patient needs.21,23,54 Alternatively, interventions with multiple components should be considered in targeting behaviour change, as they have the potential to influence PA maintenance by targeting various influential factors. Our findings have general applicability to all COPD patients completing PR, but researchers should also be mindful of context-specific factors, which could influence PA behaviour following PR in local COPD populations.

It is recommended that future research should adopt mixed methods designs, incorporating qualitative methods within randomised controlled trials to provide a more comprehensive evaluation of the factors influencing the efficacy of their interventions but also provides evidence as to how such interventions can be implemented in practice. Future qualitative research should consider and build upon the identified limitations within the studies included in this review. For example, transparency in the relationship between researcher and individual, description of study limitations, and access to participant quotations would further increase the credibility of the research in the area. It would be prudent for future studies in the area to therefore adhere to the Consolidated Criteria for Reporting Qualitative Research that facilitate critical appraisal and interpretation.

Conclusions

This systematic review identified and synthesised the data referring to the patient reported facilitators and barriers to PA following PR, which provided an in-depth understanding and insight into patient experiences regarding maintenance of PA behaviour. The results from this systematic review highlight the complexity of behaviour change, and the challenge of promoting PA following PR on a population level. The results provide clear guidance for future research design, as well as recommendations regarding the content of future interventions.

Methods

Protocol

The protocol for this review was registered on the international prospective register of systematic reviews (PROSPERO) (CRD42017058274). This review was reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)55 guidelines and Enhanced Transparency of Reporting the Synthesis of Qualitative Research framework.51


Eligibility criteria

Study design: Qualitative studies (interviews, focus groups) or mixed-methods designs which included qualitative data.

Participants: Adults with a diagnosis of COPD who have completed PR.

Exposure: Discussion of PA, which was defined as any bodily movement produced by skeletal muscles that results in energy expenditure,56 for example, experience of structured exercise such as fitness classes or walking groups, to activities of daily living such as shopping, meal preparing, or housework following PR.

Outcomes: Facilitators and barriers to PA following PR in COPD.


Searching

A comprehensive search strategy was used between February 2017 and October 2017 to identify all relevant available studies. DARE, PROSPERO, Cochrane Airways, and Cochrane Database of Systematic Reviews were searched for ongoing and published reviews. For published original studies the following databases were searched: MEDLINE, Embase, Web of Science, CINAHL, ASSIA, PsycINFO, and SPORTDiscus. An example of a full search strategy for one database (MEDLINE) is provided in the Supplementary File. Database searches were also supplemented with internet searches (e.g., Google Scholar) and contact with study authors and experts when required. Forward and backward citation tracking from included studies and review articles were also conducted to identify relevant papers. ClinicalTrials.gov and Current Controlled Trials were searched for completed and ongoing trials. DART Europe E theses, EThOS, Open Grey, The New York Academy of Medicine, ProQuest Dissertations, theses.org, and Conference Proceedings Citation Index (Web of Science) were searched for unpublished data. All references were exported and stored in EndNote.


Study screening

Two reviewers independently screened the titles and abstracts for inclusion against the defined eligibility criteria. Full-text articles were retrieved for articles that were not excluded based on title or abstract. Further independent screening of full texts was performed to determine eligibility with any disagreement between two reviewers resolved by consensus.


Data extraction

Data from the included papers was extracted by two reviewers and was completed using a bespoke data collection form for qualitative research based on the UK National Institute for Health and Clinical Excellence (NICE) universal template.57 To facilitate synthesis of qualitative data, all studies were uploaded on to NVivo 11 Pro.


Critical appraisal

Two reviewers independently performed a critical appraisal of each included study, through use of the Specialist Unit for Review Evidence (SURE) checklist (2015).52 This checklist is adapted and updated from the former Health Evidence Bulletins Wales checklist with reference to the NICE Public Health Methods Manual58 and previous versions of the Critical Appraisal Skills Programme checklists. Discrepancies were resolved through discussion between two reviewers. Studies were not excluded or weighted based on the quality assessment.


Data synthesis

Thematic analysis was the inductive approach used for synthesising the data from each study, an approach used to identify themes and patterns in qualitative research.59 This approach has previously been adopted to synthesise qualitative data in systematic reviews.59,60,61,62 Thematic synthesis was completed in three stages: the coding of text “line-by-line”, the generation of “descriptive themes”, and the generation of “analytical themes”.48 Initially, the review question was put to one side to enable an analysis that was close to the data of the original studies and prevented reviewers imposing the data on to an existing framework. Participant quotations within the findings/results section of each included study were coded according to meaning and content. A “bank” of codes were derived from the studies, and new codes were formed when necessary. Similarities and differences between the codes were explored, and codes were placed into a hierarchical structure and these represented the descriptive themes. The final stage of analysis involved engaging with the descriptive themes to answer the review question. This was an iterative process, which involved making inferences from the data about the facilitators and barriers to PA following PR, as well as considering implications regarding intervention development. To reduce bias, three reviewers independently coded the extracted data, produced descriptive themes, and reviewed and discussed analytical themes.


Data availability

No datasets were generated or analysed during the current study.

Additional information

Publisher's note: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

References

  1. 1.

    Global Initiative for Chronic Obstructive Lung Disease (GOLD). From the global strategy for the diagnosis, management and prevention of COPD. http://goldcopd.org (2017).

  2. 2.

    Vorrink, S. N., Kort, H. S., Troosters, T. & Lammers, J.-W. J. Level of daily physical activity in individuals with COPD compared with healthy controls. Respir. Res. 12, 33 (2011).

  3. 3.

    Pitta, F. et al. Characteristics of physical activities in daily life in chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 171, 972–977 (2005).

  4. 4.

    Arne, M. et al. Factors associated with good self-rated health and quality of life in subjects with self-reported COPD. Int. J. Chron. Obstruct. Pulmon. Dis. 6, 511–519 (2011).

  5. 5.

    Watz, H. et al. An official European Respiratory Society statement on physical activity in COPD. Eur. Respir. J. 44, 1521–1537 (2014).

  6. 6.

    Decramer, M., Janssens, W. & Miravitlles, M. Chronic obstructive pulmonary disease. Lancet 379, 1341–1351 (2012).

  7. 7.

    Vestbo, J. et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 187, 347–365 (2013).

  8. 8.

    Waschki, B. et al. Physical activity is the strongest predictor of all-cause mortality in patients with COPD: a prospective cohort study. Chest 140, 331–342 (2011).

  9. 9.

    Vaes, A. W. et al. Changes in physical activity and all-cause mortality in COPD. Eur. Respir. J. 44, 1199–1209 (2014).

  10. 10.

    Pitta, F. et al. Physical activity and hospitalization for exacerbation of COPD. Chest 129, 536–544 (2006).

  11. 11.

    Garcia-Aymerich, J., Lange, P., Serra, I., Schnohr, P. & Antó, J. M. Time-dependent confounding in the study of the effects of regular physical activity in chronic obstructive pulmonary disease: an application of the marginal structural model. Ann. Epidemiol. 18, 775–783 (2008).

  12. 12.

    Garcia-Rio, F. et al. Prognostic value of the objective measurement of daily physical activity in patients with COPD. Chest 142, 338–346 (2012).

  13. 13.

    Benzo, R. P. et al. Physical activity, health status and risk of hospitalization in patients with severe chronic obstructive pulmonary disease. Respir. Int. Rev. Thorac. Dis. 80, 10–18 (2010).

  14. 14.

    Gimeno-Santos, E. et al. Determinants and outcomes of physical activity in patients with COPD: a systematic review. Thorax 69, 731–739 (2014).

  15. 15.

    Spruit, M. A. et al. An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation. Am. J. Respir. Crit. Care Med. 188, e13–e64 (2013).

  16. 16.

    McCarthy, B. et al. Pulmonary rehabilitation for chronic obstructive pulmonary disease. Cochrane Database Syst. Rev. 3, CD003793 (2015).

  17. 17.

    Mesquita, R. et al. Changes in physical activity and sedentary behaviour following pulmonary rehabilitation in patients with COPD. Respir. Med. 126, 122–129 (2017).

  18. 18.

    Ng, L. W. C., Mackney, J., Jenkins, S. & Hill, K. Does exercise training change physical activity in people with COPD? A systematic review and meta-analysis. Chron. Respir. Dis. 9, 17–26 (2012).

  19. 19.

    Mantoani, L. C., Rubio, N., McKinstry, B., MacNee, W. & Rabinovich, R. A. Interventions to modify physical activity in patients with COPD: a systematic review. Eur. Respir. J. 48, 69–81 (2016).

  20. 20.

    Lahham, A., McDonald, C. F. & Holland, A. E. Exercise training alone or with the addition of activity counseling improves physical activity levels in COPD: a systematic review and meta-analysis of randomized controlled trials. Int. J. Chron. Obstruct. Pulmon. Dis. 11, 3121–3136 (2016).

  21. 21.

    Beauchamp, M. K., Evans, R., Janaudis-Ferreira, T., Goldstein, R. S. & Brooks, D. Systematic review of supervised exercise programs after pulmonary rehabilitation in individuals with COPD. Chest 144, 1124–1133 (2013).

  22. 22.

    Rochester, C. L. & Spruit, M. A. Maintaining the benefits of pulmonary rehabilitation. The holy grail. Am. J. Respir. Crit. Care Med. 195, 548–551 (2017).

  23. 23.

    Spruit, M. A., Pitta, F., McAuley, E., ZuWallack, R. L. & Nici, L. Pulmonary rehabilitation and physical activity in patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 192, 924–933 (2015).

  24. 24.

    de Sousa Pinto, J. M. et al. Chronic obstructive pulmonary disease patients’ experience with pulmonary rehabilitation: a systematic review of qualitative research. Chron. Respir. Dis. 10, 141–157 (2013).

  25. 25.

    Thorpe, O., Johnston, K. & Kumar, S. Barriers and enablers to physical activity participation in patients with COPD: a systematic review. J. Cardiopulm. Rehabil. Prev. 32, 359–369 (2012).

  26. 26.

    Kwasnicka, D., Dombrowski, S. U., White, M. & Sniehotta, F. Theoretical explanations for maintenance of behaviour change: a systematic review of behaviour theories. Health Psychol. Rev. 10, 277–296 (2016).

  27. 27.

    Hoaas, H., Andreassen, H. K., Lien, L. A., Hjalmarsen, A. & Zanaboni, P. Adherence and factors affecting satisfaction in long-term telerehabilitation for patients with chronic obstructive pulmonary disease: a mixed methods study. BMC Med. Inform. Decis. Mak. 16, 26 (2016).

  28. 28.

    Hoaas, H., Morseth, B., Holland, A. E. & Zanaboni, P. Are physical activity and benefits maintained after long-term telerehabilitation in COPD? Int. J. Telerehabilitation 8, 39–48 (2016).

  29. 29.

    Beauchamp, M. K. et al. Feasibility and acceptability of a community based maintenance exercise program for people with COPD. Can. Respir. J. 19, e42 (2012).

  30. 30.

    Desveaux, L., Rolfe, D., Beauchamp, M., Goldstein, R. & Brooks, D. Participant experiences of a community-based maintenance program post-pulmonary rehabilitation. Chron. Respir. Dis. 11, 23–30 (2014).

  31. 31.

    Langley-Johnson, C. A. et al. P50 facilitation of continued exercise via patient volunteers with chronic obstructive pulmonary disease (COPD) following a pulmonary rehabilitation programme: a feasibility study. Thorax 65, A98–A98 (2010).

  32. 32.

    Matheson, L. et al. P44 COPD patients derived benefits from attending PR: ‘this has given me my life back’. Thorax 65, A95–A95 (2010).

  33. 33.

    Camp, P. G., Appleton, J. & Reid, W. D. Quality of life after pulmonary rehabilitation: assessing change using quantitative and qualitative methods. Phys. Ther. 80, 986–995 (2000).

  34. 34.

    Desveaux, L. et al. ‘We are all there for the same purpose’: support for an integrated community exercise program for older adults with HF and COPD. Heart Lung J. Crit. Care 46, 308–312 (2017).

  35. 35.

    Halding, A.-G. & Heggdal, K. Patients’ experiences of health transitions in pulmonary rehabilitation. Nurs. Inq. 19, 345–356 (2012).

  36. 36.

    Sundfør, I. E. ‘But I May Be Vacuuming…’: A Qualitative Study on Changing Working Habits and Awareness of Energy-Saving Working Methods for People with COPD. Master's Thesis, http://hdl.handle.net/10642/556 (Oslo University College, 2010).

  37. 37.

    Stewart, K. F. J. et al. Maintenance of a physically active lifestyle after pulmonary rehabilitation in patients with COPD: a qualitative study toward motivational factors. J. Am. Med. Dir. Assoc. 15, 655–664 (2014).

  38. 38.

    Hogg, L., Grant, A., Garrod, R. & Fiddler, H. People with COPD perceive ongoing, structured and socially supportive exercise opportunities to be important for maintaining an active lifestyle following pulmonary rehabilitation: a qualitative study. J. Physiother. 58, 189–195 (2012).

  39. 39.

    Lewis, R. & Cramp, F. Facilitators and barriers to exercise maintenance in chronic obstructive pulmonary disease: patient views. Physiother. Pract. Res. 31, 19–24 (2010).

  40. 40.

    Rodgers, S., Dyas, J., Molyneux, A. W. P., Ward, M. J. & Revill, S. M. Evaluation of the information needs of patients with chronic obstructive pulmonary disease following pulmonary rehabilitation: a focus group study. Chron. Respir. Dis. 4, 195–203 (2007).

  41. 41.

    Williams, V., Bruton, A., Ellis-Hill, C. & McPherson, K. The effect of pulmonary rehabilitation on perceptions of breathlessness and activity in COPD patients: a qualitative study. Prim. Care Respir. J. 19, 45–51 (2010).

  42. 42.

    Norweg, A., Bose, P., Snow, G. & Berkowitz, M. E. A pilot study of a pulmonary rehabilitation programme evaluated by four adults with chronic obstructive pulmonary disease. Occup. Ther. Int. 15, 114–132 (2008).

  43. 43.

    Rabinowitz, M. C. Stories of Exercise Noncompliane among Patients with Chronic Obstructive Pulmonary Disease after Completion of Pulmonary Rehabilitation. PhD Thesis, http://link.library.missouri.edu/portal/Stories-of-exercise-noncompliance-among-patients/b2ze39d84hw/ (Adelphi University, 1998).

  44. 44.

    Zakrisson, A.-B., Theander, K. & Anderzén-Carlsson, A. How life turned out one year after attending a multidisciplinary pulmonary rehabilitation programme in primary health care. Prim. Health Care Res. Dev. 15, 302–311 (2014).

  45. 45.

    Granger, C. L. et al. Understanding factors influencing physical activity and exercise in lung cancer: a systematic review. Support. Care Cancer 25, 983–999 (2017).

  46. 46.

    Michie, S., Atkins, L. & West, R. The behaviour change wheel: a guide to designing interventions. (London, Silverback publishing, 2014).

  47. 47.

    Britten, N. et al. Using meta ethnography to synthesise qualitative research: a worked example. J. Health Serv. Res. Policy 7, 209–215 (2002).

  48. 48.

    Thomas, J. & Harden, A. Methods for the thematic synthesis of qualitative research in systematic reviews. BMC Med. Res. Methodol. 8, 45 (2008).

  49. 49.

    Campbell, R. et al. Evaluating meta-ethnography: a synthesis of qualitative research on lay experiences of diabetes and diabetes care. Soc. Sci. Med. 56, 671–684 (2003).

  50. 50.

    Sandelowski, M. & Barroso, J. Handbook for synthesizing qualitative research. (New York, Springer, 2007).

  51. 51.

    Tong, A., Flemming, K., McInnes, E., Oliver, S. & Craig, J. Enhancing transparency in reporting the synthesis of qualitative research: ENTREQ. BMC Med. Res. Methodol. 12, 181 (2012).

  52. 52.

    Specialist Unit for Review Evidence (SURE). Questions to assist with the critical appraisal of qualitative studies. http://www.cardiff.ac.uk/specialist-unit-for-review-evidence/resources/critical-appraisalchecklists (2015).

  53. 53.

    Dixon-Woods, M. et al. Appraising qualitative research for inclusion in systematic reviews: a quantitative and qualitative comparison of three methods. J. Health Serv. Res. Policy 12, 42–47 (2007).

  54. 54.

    Effing, T. et al. Self-management education for patients with chronic obstructive pulmonary disease. Cochrane Database of Syst. Rev. 4, CD002990 (2007).

  55. 55.

    Moher, D. et al. Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement. Syst. Rev. 4, 1 (2015).

  56. 56.

    Caspersen, C. J., Powell, K. E. & Christenson, G. M. Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. Public Health Rep. 100, 126–131 (1985).

  57. 57.

    National Collaborating Centre for Mental Health (UK). Dementia: A NICE-SCIE Guideline on Supporting People With Dementia and Their Carers in Health and Social Care. (British Psychological Society, 2007).

  58. 58.

    National Institute for Health and Care Excellence: The guidelines manual. Process and methods: https://www.nice.org.uk/process/pmg6/chapter/introduction (2012).

  59. 59.

    Braun, V. & Clarke, V. Using thematic analysis in psychology. Qual. Res. Psychol. 3, 77–101 (2006).

  60. 60.

    Franco, M. R. et al. Older people’s perspectives on participation in physical activity: a systematic review and thematic synthesis of qualitative literature. Br. J. Sports Med. 49, 1268–1276 (2015).

  61. 61.

    Morton, R. L., Tong, A., Howard, K., Snelling, P. & Webster, A. C. The views of patients and carers in treatment decision making for chronic kidney disease: systematic review and thematic synthesis of qualitative studies. Br. Med. J. 340, c112 (2010).

  62. 62.

    Joseph-Williams, N., Elwyn, G. & Edwards, A. Knowledge is not power for patients: a systematic review and thematic synthesis of patient-reported barriers and facilitators to shared decision making—ScienceDirect. Patient Educ. Couns. 94, 291–309 (2014).

Download references

Acknowledgements

We would like to thank Marishona Ortega (Senior Academic Subject Librarian) for her support in the development of the search strategy in this review. We wish to acknowledge the co-operation of authors of some of the included studies (Hoaas; Sundfør; Stewart; Desveaux; Beauchamp) in this review for responding to requests for additional study information.

Author information

Affiliations

  1. Lincoln Institute for Health, University of Lincoln, Lincoln, UK

    • Hayley Robinson
    • , Ffion Curtis
    • , Christopher Bridle
    •  & Arwel W. Jones
  2. Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK

    • Veronika Williams

Authors

  1. Search for Hayley Robinson in:

  2. Search for Veronika Williams in:

  3. Search for Ffion Curtis in:

  4. Search for Christopher Bridle in:

  5. Search for Arwel W. Jones in:

Contributions

All authors (H.R., V.W., F.C., C.B., A.W.J.) contributed to study conception and protocol of the review. H.R. and A.W.J. performed searching and screening of results. H.R., V.W., and A.W.J. conducted data analysis (thematic synthesis) and interpretation of data. H.R. drafted the manuscript and all authors provided critical revisions and editing of the manuscript.

Competing interests

The authors declare no competing interests.

Corresponding author

Correspondence to Hayley Robinson.

Electronic supplementary material

About this article

Publication history

Received

Revised

Accepted

Published

DOI

https://doi.org/10.1038/s41533-018-0085-7