We reveal that a family of plant stress-induced signalling peptides, SERINE-RICH ENDOGENOUS PEPTIDES (SCOOPs), is much larger than originally thought, and identify key proteases required for their biogenesis. We find that impairing SCOOP biogenesis phenocopies a mutant of the SCOOP receptor MALE DISCOVERER 1-INTERACTING RECEPTOR-LIKE KINASE 2 (MIK2).
This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$29.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 digital issues and online access to articles
$119.00 per year
only $9.92 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Gully, K. et al. The SCOOP12 peptide regulates defense response and root elongation in Arabidopsis thaliana. J. Exp. Bot. 70, 1349–1365 (2019). A paper reporting the discovery of SCOOP peptides.
Rhodes, J. et al. Perception of a divergent family of phytocytokines by the Arabidopsis receptor kinase MIK2. Nat. Commun. https://doi.org/10.1038/s41467-021-20932-y (2021). A paper describing the identification of MIK2 as the SCOOP receptor.
Hou, S. et al. The Arabidopsis MIK2 receptor elicits immunity by sensing a conserved signature from phytocytokines and microbes. Nat. Commun. 12, 5494 (2021). A paper describing the identification of MIK2 as the SCOOP receptor.
Van der Does, D. et al. The Arabidopsis leucine-rich repeat receptor kinase MIK2/LRR-KISS connects cell wall integrity sensing, root growth and response to abiotic and biotic stresses. PLoS Genet. 13, e1006832 (2017). A paper describing the multiple functions of MIK2 in different stress responses.
Neukermans, J. et al. ARACINs, Brassicaceae-specific peptides exhibiting antifungal activities against necrotrophic pathogens in. Arabidopsis. Plant Physiol. 167, 1017–1029 (2015). A paper describing members of the SCOOP family as anti-microbial peptides.
Additional information
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
This is a summary of: Yang, H. et al. Subtilase-mediated biogenesis of the expanded family of SERINE RICH ENDOGENOUS PEPTIDES. Nat. Plants https://doi.org/10.1038/s41477-023-01583-x (2023).
Rights and permissions
About this article
Cite this article
A large family of stress-regulated SCOOP peptides and their processing by subtilases. Nat. Plants 9, 1954–1955 (2023). https://doi.org/10.1038/s41477-023-01584-w
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41477-023-01584-w
