Microscopic visualization of the ARP2/3 complex showed that it colocalizes with peroxisomes in Arabidopsis thaliana and tobacco cells in vivo. Colocalization with an autophagy marker and analysis of peroxisomes in autophagy-mutant or ARP2/3-mutant lines demonstrated that ARP2/3 facilitates peroxisome degradation by the autophagic pathway, that is, pexophagy.
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This is a summary of: Martinek, J. et al. ARP2/3 complex associates with peroxisomes to participate in pexophagy in plants. Nat. Plants https://doi.org/10.1038/s41477-023-01542-6 (2023).
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Actin remodelling and autophagy meet at the peroxisome. Nat. Plants 9, 1789–1790 (2023). https://doi.org/10.1038/s41477-023-01547-1
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DOI: https://doi.org/10.1038/s41477-023-01547-1