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Plant resistosomes

Wheeling in a new era in plant immunity

Pathogen perception in plants is mediated by immune receptors that detect specific pathogen molecules. Members of one diverse receptor family that occurs in all land plants form a structurally conserved activation complex with a shared signalling mechanism.

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Fig. 1: The activated resistosome complexes of Sr35 and ZAR1 share striking similarities in structure and function, as well as a conserved steric clash model mediating activation.

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Correspondence to Peter N. Dodds.

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Outram, M.A., Dodds, P.N. Wheeling in a new era in plant immunity. Nat. Plants 8, 1142–1143 (2022). https://doi.org/10.1038/s41477-022-01257-0

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