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EPIGENETICS

The chromatin will never forget

A chromatin-based, RNA interference (RNAi)-independent mechanism re-establishes DNA methylation on heterochromatic transposable elements that lost silent marks in previous generations. Multiple factors including CG methylation and H2A.W replacement influence the efficiency of this methylation reprogramming mechanism.

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Fig. 1: RNAi-independent de novo DNA methylation at TE genes.

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Correspondence to Jixian Zhai.

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Yu, Y., Zhai, J. The chromatin will never forget. Nat. Plants 6, 1396–1397 (2020). https://doi.org/10.1038/s41477-020-00803-y

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