Pathogen perception triggers a monomeric nucleotide-binding leucine-rich plant immune receptor to form a pentameric wheel-like complex termed a resistosome, with the N-terminal α helices forming a funnel-shaped structure that may perturb plasma membrane integrity to cause hypersensitive cell death.
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References
Jones, J. D., Vance, R. E. & Dangl, J. L. Science 354, aaf6395 (2016).
Bentham, A., Burdett, H., Anderson, P. A., Williams, S. J. & Kobe, B. Ann. Bot. 119, 689–702 (2017).
Wang, J. et al. Science 364, eaav5868 (2019).
Wang, J. et al. Science 364, eaav5870 (2019).
Seuring, C. et al. PLoS Biol. 10, e1001451 (2012).
Cai, X. et al. Cell 156, 1207–1222 (2014).
Urbach, J. M. & Ausubel, F. M. Proc. Natl Acad. Sci. USA 114, 1063–1068 (2017).
Le Fevre, R., Evangelisti, E., Rey, T. & Schornack, S. Annu. Rev. Cell Dev. Biol. 31, 201–229 (2015).
Adachi, H. & Tsuda, K. New Phytol. 221, 1676–1678 (2019).
Betsuyaku, S. et al. Plant Cell Physiol. 59, 8–16 (2018).
Adachi, H., Derevnina, L. & Kamoun, S. Zenodo https://doi.org/10.5281/zenodo.2560083 (2019).
Wu, C.-H., Derevnina, L. & Kamoun, S. Science 360, 1300–1301 (2018).
Wu, C. ‐H. et al. Proc. Natl Acad. Sci. USA 114, 8113–8118 (2017).
Li, J. et al. Mol. Plant 12, 248–262 (2019).
Tenthorey, J. L. Science 358, 888–893 (2017).
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Adachi, H., Kamoun, S. & Maqbool, A. A resistosome-activated ‘death switch’. Nat. Plants 5, 457–458 (2019). https://doi.org/10.1038/s41477-019-0425-9
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DOI: https://doi.org/10.1038/s41477-019-0425-9
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