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HERBICIDE RESISTANCE

Raising the BAR of specificity

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Phosphinothricin resistance is a widely used trait in plant science research and agriculture. The BAR resistance gene that inactivates phosphinothricin has now been shown to produce two non-specific metabolites in planta. An engineered BAR resistance gene with no detectable off-target activity is developed to address this issue.

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Fig. 1: Activity of BAR and engineered BAR enzyme.

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Correspondence to Sarah E. O’Connor.

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The author declares no competing financial interests.

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O’Connor, S.E. Raising the BAR of specificity. Nature Plants 3, 924–925 (2017). https://doi.org/10.1038/s41477-017-0074-9

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