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A prospective study comparing mini-invasive and conventional canaliculotomy of punctum-sparing canaliculotomy for primary canaliculitis treatment

Abstract

Purpose

To compare outcomes of mini-invasive canaliculotomy with those of conventional canaliculotomy conducted using the punctum-sparing approach for the treatment of primary canaliculitis.

Methods

A prospective, comparative, and interventional case series study was conducted on 118 individuals with unilateral inferior primary canaliculitis. These patients were randomly divided into two groups, each with 59 cases. Group A underwent mini-invasive canaliculotomy (minor incision ~3 mm), whereas group B received conventional canaliculotomy (long incision ~6–8 mm). Punctum-sparing and canaliculus-reconstructing procedure was used to treat all patients. Both groups had silicone tube intubations and were retained in the lacrimal passages for one month. Both groups’ surgical success rates and postoperative complications were measured at the last follow-up of 12 months after surgery.

Results

A total of 108 patients were finally included in the study, 53 in group A and 55 in group B. There were 79 females and 29 males with a median age of 57 ± 13.4 years. The anatomical success rates for groups A and B were 96.2% and 92.7% (P = 0.679), respectively. Functional success rate was accomplished by considerably more patients in group A (50/53, 94.3%) compared to group B (45/55, 81.8%) (P = 0.046). No recurrences were seen during follow-up visits in any of the participants.

Conclusions

The two procedures employed in this study to treat primary canaliculitis achieves excellent clinical effects with no incidence of recurrence. The mini-invasive canaliculotomy is worthy to be recommended for its higher functional success rate with mini-invasion of canaliculus and intact lacrimal punctum.

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Fig. 1: Depicts the steps of the method of mini-invasive canaliculotomy with curettage.
Fig. 2: The procedure for conventional canaliculotomy with curettage is illustrated.
Fig. 3: The signs and symptoms of primary canaliculitis and the surgical results of a mini-invasive canaliculotomy with curettage are shown.

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Data availability

The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.

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Acknowledgements

All work was performed at Eye Hospital of Wenzhou Medical University. The authors would like to thank Dr Jieliang Shi and Ende Wu for providing medical treatment to the patients and collecting clinical data.

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Authors

Contributions

MW wrote the paper, submitted the study, and collected clinical data. BY conducted the survey, took responsibility for the integrity of the data and the accuracy of the analysis, and revised the paper. WW planned and initiated the study. YM provided medical care for the patients and collected the clinical data. YT wrote the statistical analysis plan, designed data collection, and analyzed the data.

Corresponding authors

Correspondence to Wencan Wu or Bo Yu.

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Wang, M., Ma, Y., Tu, Y. et al. A prospective study comparing mini-invasive and conventional canaliculotomy of punctum-sparing canaliculotomy for primary canaliculitis treatment. Eye 37, 2289–2293 (2023). https://doi.org/10.1038/s41433-022-02333-7

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  • DOI: https://doi.org/10.1038/s41433-022-02333-7

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