Reference to original study:
Guidi G, Casini G, Ripandelli G, Piaggi P, Lucche FD, Sartini M, Loiudice P, Nasini F, Stripe M, Lazzeri S. Residual intraretinal edema after 25-gauge vitrectomy and macular pucker removal: Is intraoperative sustained-release dexamethasone a real treatment option? Retina. 2018;38:993–9. https://doi.org/10.1097/IAE.0000000000001627.
This randomised controlled trial aimed to investigate the efficacy and safety of intraoperative slow-release dexamethasone implant in vitrectomy plus OZRUDEX implant vs. vitrectomy without OZRUDEX implant for the treatment of idiopathic macular pucker. It found that intraoperative sustained-release dexamethasone implant, a powerful anti-inflammatory agent with significant efficacy in vitrectomized eyes, did not result in a significant change in macular thickness and volume compared with the vitrectomy alone without dexamethasone implant at 6-month follow-up. ERM epiretinal membrane, MP macular pucker.
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Al-Zubaidy, M., Ghareeb, A., Mostafa, I. et al. Infographic: residual intraretinal edema after 25-gauge vitrectomy and macular pucker removal: Is intraoperative sustained-release dexamethasone a real treatment option?. Eye 36, 5–6 (2022). https://doi.org/10.1038/s41433-021-01533-x
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DOI: https://doi.org/10.1038/s41433-021-01533-x
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