Abstract
Data sources A preliminary, randomised, prospective, controlled clinical trial of patients managed with two regenerative endodontic procedures, revitalisation and a platelet-rich fibrin (PRF)-based technique, in the treatment of mature permanent teeth with necrotic pulps.
Study selection Twenty patients with mature necrotic anterior teeth with large periapical lesions treated with the blood clot and a PRF-based techniques for revitalisation. Periradicular healing and pulp sensibility was assessed at 6 and 12 months after treatment.
Results Significant periradicular radiographic healing and sensibility was reported at 6 and 12 months.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 4 print issues and online access
$259.00 per year
only $64.75 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Glynis A, Foschi F, Kefalou I, Koletsi D, Tzanetakis G N. Regenerative Endodontic Procedures for the Treatment of Necrotic Mature Teeth with Apical Periodontitis: A Systematic Review and Meta-analysis of Randomized Controlled Trials. J Endod 2021; 47: 873-882.
Youssef A, Ali M, ElBolok A, Hassan R. Regenerative endodontic procedures for the treatment of necrotic mature teeth: A preliminary randomized clinical trial. Int Endod J 2022; 55: 334-346.
Seltzer S, Bender I B, Ziontz M. The Dynamics of Pulp Inflammation: Correlations between Diagnostic Data and Actual Histologic Findings in the Pulp. Oral Surg Oral Med Oral Pathol 1963; 16: 969-977.
Seltzer S, Bender I B, Ziontz M. The dynamics of pulp inflammation: correlations between diagnostic data and actual histologic findings in the pulp. Oral Surg Oral Med Oral Pathol 1963; 16: 846-871.
Mumford J M. Pain perception threshold on stimulating human teeth and the histological condition of the pulp. Br Dent J 1967; 123: 427-433.
Dummer P M, Hicks R, Huws D. Clinical signs and symptoms in pulp disease. Int Endod J 1980; 13: 27-35.
Lin J, Chandler N P. Electric pulp testing: a review. Int Endod J 2008; 41: 365-374.
Nakashima M, Iohara K, Murakami M et al. Pulp regeneration by transplantation of dental pulp stem cells in pulpitis: a pilot clinical study. Stem Cell Res Ther 2017; 8: 61.
Närhi M, Virtanen A, Kuhta J, Huopaniemi T. Electrical stimulation of teeth with a pulp tester in the cat. Scand J Dent Res 1979; 87: 32-38.
Jafarzadeh H, Abbott P V. Review of pulp sensibility tests. Part II: electric pulp tests and test cavities. Int Endod J 2010; 43: 945-958.
Bender I B, Landau M A, Fonsecca S, Trowbridge H O. The optimum placement-site of the electrode in electric pulp testing of the 12 anterior teeth. J Am Dent Assoc 1989; 118: 305-310.
Lilja J. Sensory differences between crown and root dentin in human teeth. Acta Odontol Scand 1980; 38: 285-291.
Cailleteau J G, Ludington J R. Using the electric pulp tester with gloves: a simplified approach. J Endod 1989; 15: 80-81.
Nam K C, Ahn S H, Cho J H, Kim D W, Lee S J. Reduction of excessive electrical stimulus during electric pulp testing. Int Endod J 2005; 38: 544-549.
Orstavik D, Kerekes K, Eriksen H M. The periapical index: a scoring system for radiographic assessment of apical periodontitis. Endod Dent Traumatol 1986; 2: 20-34.
Estrela C, Bueno M R, Azevedo B C, Azevedo J R, Pecora J D. A new periapical index based on cone beam computed tomography. J Endod 2008; 34: 1325-1331.
Boubaris M, Chan K L, Zhao W et al. A Novel Volume-based Cone-beam Computed Tomographic Periapical Index. J Endod 2021; 47: 1308-1313.
George R, Nair R G, Manakil J, Cosson J. Are we missing something? Imaging challenge - A case report. Endod Pract Today 2016; 10: 31-34.
Fontenele R C, Nascimento E H L, Gaeta-Araujo H, Cardelli L O A, Freitas D Q. Which factors related to apical radiolucency may influence its radiographic detection? A study using CBCT as reference standard. Restor Dent Endod 2021; DOI: 10.5395/rde.2021.46.e43.
Author information
Authors and Affiliations
Ethics declarations
The author declares no conflicts of interest.
Rights and permissions
About this article
Cite this article
George, R. Quality of techniques used to assess clinical outcomes of regenerative endodontic treatment in necrotic mature teeth. Evid Based Dent 23, 98–99 (2022). https://doi.org/10.1038/s41432-022-0806-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/s41432-022-0806-1