Abstract
Data sources Cochrane Central Register of Controlled Trials (CENTRAL), Medline (Ovid), Embase, Web of Science, Latin American & Caribbean Health Sciences Literature (LILACS) and SIGLE database.
Study selection Randomised controlled trials (RCTs), controlled clinical trials (CCTs), cohort studies, case-control studies and cross-sectional studies.
Data extraction and synthesis Two reviewers screened papers independently and assessed the risk of bias. Data categorised based on the study design. The primary outcome was the odds ratio (OR)/relative risk (RR) and confidence interval (CI) for hypertension in individuals with periodontitis.
Results Diagnoses of moderate-to-severe (OR = 1.22; 95% CI: 1.10-1.35) and severe periodontitis (OR = 1.49; 95% CI: 1.09-2.05) were associated with hypertension. Diagnosis of periodontitis increased odds of occurring hypertension (OR = 1.68; 95% CI: 0.85-3.35). Patients with periodontitis exhibited higher mean systolic (weighted mean difference [WMD] of 4.49 mmHg; 95% CI: 2.88-6.11) and diastolic blood pressures (2.03 mmHg; 95% CI: 1.25-2.81). There was inconclusive evidence that periodontal therapy reduces blood pressure (3-12.5 mmHg of systolic and 0-10 mmHg of diastolic blood pressures).
Conclusions Periodontitis could be associated with increased risk of hypertension. Further, the management of periodontitis could impact on the management of hypertension. However, there is still a need for more high-quality research.
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References
Williams B, Mancia G, Spiering W et al. 2018 ESC/ESH Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH). J Hypertens 2018; 39: 3021-3104.
Kassebaum N, Smith A, Bernabé E et al. Global, regional, and national prevalence, incidence, and disability-adjusted life years for oral conditions for 195 countries, 1990-2015: a systematic analysis for the global burden of diseases, injuries, and risk factors. J Dent Res 2017; 96: 380-387.
Listl S, Galloway J, Mossey P, Marcenes W. Global economic impact of dental diseases. J Dent Res 2015; 94: 1355-1361.
Martin-Cabezas R, Seelam N, Petit C et al. Association between periodontitis and arterial hypertension: A systematic review and meta-analysis. Am Heart J 2016; 180: 98-112.
Tsioufis C, Kasiakogias A, Thomopoulos C, Stefanadis C. Periodontitis and blood pressure: the concept of dental hypertension. Atherosclerosis 2011; 219: 1-9.
Lucia Macedo Paizan M, Fernando Vilela-Martin J. Is there an association between periodontitis and hypertension? Curr Cardiol Rev 2014; 10: 355-361.
Muñoz Aguilera E, Suvan J, Buti J et al. Periodontitis is associated with hypertension: a systematic review and meta-analysis. Cardiovasc Res 2020; 116: 28-39.
Sheiham A, Watt R G. The common risk factor approach: a rational basis for promoting oral health. Community Dent Oral Epidemiol 2000; 28: 399-406.
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Sofi-Mahmudi, A. Is periodontitis associated with hypertension?. Evid Based Dent 21, 132–133 (2020). https://doi.org/10.1038/s41432-020-0137-z
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DOI: https://doi.org/10.1038/s41432-020-0137-z
