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Managing fluid balance and nutritional status in a short bowel syndrome patient awaiting intestinal transplant: a case report

Abstract

Background

Despite being a long-term therapy for patients with short bowel syndrome (SBS), subcutaneous injections of teduglutide promote the regeneration of the gastrointestinal tract. Such cases are particularly concerning for patients with residual small bowel.

Methods

In this report, we present a case of an SBS patient with only 5 cm of remaining small bowel and a high-output duodenal stoma, who was treated with teduglutide.

Results

The initiation of teduglutide injections in our patient resulted in a reduction of stoma output, improvement in the patient’s nutritional status, regulation of fluid balance, and stabilization of their clinical condition.

Conclusions

This case suggests that subcutaneous injections of teduglutide, when combined with appropriate nutritional care, can effectively treat high-output stomas, even in cases where the small bowel is nearly absent.

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Authors and Affiliations

Authors

Contributions

AP, VV, and DK contributed to the acquisition and analysis of clinical data, participated in the literature review, and played a significant role in drafting and revising the manuscript; ZB, AP, KE, TA, and VV discussed and edited the manuscript. All authors have read and agreed to the final version of the manuscript.

Corresponding author

Correspondence to Dimitrios Karayiannis.

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The authors declare no competing interests.

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Bouloubasi, Z., Karayiannis, D., Papadopoulou, A. et al. Managing fluid balance and nutritional status in a short bowel syndrome patient awaiting intestinal transplant: a case report. Eur J Clin Nutr (2024). https://doi.org/10.1038/s41430-024-01405-z

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  • DOI: https://doi.org/10.1038/s41430-024-01405-z

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