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Nutrition and Health (including climate and ecological aspects)

Association of plant-based dietary patterns in first trimester of pregnancy with gestational weight gain: results from a prospective birth cohort

Abstract

Background/objectives

Plant-based dietary patterns are becoming more popular worldwide. We aimed to examine the relationship between plant-based dietary patterns and the risk of inadequate or excessive gestational weight gain (GWG) in Iranian pregnant women.

Methods

We prospectively followed 657 pregnant women in Iran. Adherence to the plant-based diet, represented by plant-based (PDI), healthy (hPDI) and unhealthy plant-based (uPDI) dietary indexes was evaluated by applying a 90-item food frequency questionnaire during the first trimester of pregnancy. Multivariable-adjusted Cox proportional-hazards regression model was used to compute hazard ratios (HRs) and 95% confidence intervals (CIs) across quartiles of plant-based diet scores.

Results

Over 25,562 person-weeks of follow-up, we documented 106 and 294 participants with inadequate and excessive GWG, respectively. We found a strong inverse association between adherence to the PDI and inadequate GWG after adjustment for demographic and confounding variables. Women in the highest quartile of the PDI had 50% lower risk of inadequate GWG than those in the lowest quartile (adjusted HR: 0.50; 95%CI 0.29, 0.89; P = 0.02). No significant association was found between hPDI and uPDI and inadequate GWG. There was no association between PDI, hPDI, and uPDI and the risk of excessive GWG.

Conclusions

Greater adherence to a plant-based diet during the first trimester of pregnancy may be associated with a lower risk of inadequate GWG. This finding needs to be confirmed in larger cohort studies, considering other pregnancy outcomes such as birth weight and the potential changes across the trimester in terms of food types and quantity.

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Data availability

The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

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Funding

This study was supported by Semnan University of Medical Sciences (Grant number: 1908).

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Authors and Affiliations

Authors

Contributions

AJ, SS-B, and MMK conceived and designed th study, SZM, HM and AE contributed to the data gathering, SZM and AJ analyzed the data, SZM, HM, AE, and AJ wrote the first draft of the manuscript, SS-B and MMK critically revised the manuscript. All authors have read and approved the final manuscript. SS-B had primary responsibility for final content.

Corresponding author

Correspondence to Sakineh Shab-Bidar.

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All authors declare no conflict of interest.

Ethics approval and consent to participate

This study was conducted according to the guidelines laid down in the Declaration of Helsinki and all procedures involving research study participants were approved by the ethics committee of Semnan University of Medical Sciences. Written informed consent was obtained from all subjects/patients.

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Jayedi, A., Zeraattalab-Motlagh, S., Moosavi, H. et al. Association of plant-based dietary patterns in first trimester of pregnancy with gestational weight gain: results from a prospective birth cohort. Eur J Clin Nutr (2023). https://doi.org/10.1038/s41430-023-01275-x

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  • DOI: https://doi.org/10.1038/s41430-023-01275-x

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