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Diet- but not exercise-induced iso-energetic deficit induces compensatory appetitive responses

Abstract

Although physical exercise and dietary restriction can be both used to induce energy deficits, they have been suggested to favor different compensatory appetitive responses. While dietary restriction might favor increased subsequent energy intake and appetite sensations, such compensatory responses have not been observed after a similar deficit by exercise. The present work provides a first overview of the actual evidences discussing the effects of iso-energetic deficits induced by exercise versus dietary restriction on subsequent energy intake, appetite sensations, and on the potentially involved hedonic and physiological mechanisms.

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Fig. 1: Appetitive (subsequent energy intake, appetite sensations, food reward, and appetite-related hormones) responses to iso-energetic energy deficits induced either by dietary restriction (Def-EI) or exercise (Def-EX), compared to a control condition (CON).

References

  1. 1.

    Thivel D, Finlayson G, Blundell JE. Homeostatic and neurocognitive control of energy intake in response to exercise in pediatric obesity: a psychobiological framework. Obes Rev. 2019;20:316–24.

    CAS  Article  Google Scholar 

  2. 2.

    Blundell JE, Gibbons C, Caudwell P, Finlayson G, Hopkins M. Appetite control and energy balance: impact of exercise. Obes Rev. 2015;16:67–76.

    Article  Google Scholar 

  3. 3.

    Schubert MM, Desbrow B, Sabapathy S, Leveritt M. Acute exercise and subsequent energy intake. a meta-analysis. Appetite 2013;63:92–104.

    Article  Google Scholar 

  4. 4.

    Donnelly JE, Herrmann SD, Lambourne K, Szabo AN, Honas JJ, Washburn RA. Does increased exercise or physical activity alter ad-libitum daily energy intake or macronutrient composition in healthy adults? A systematic review. PLoS One. 2014;9:e83498.

    Article  Google Scholar 

  5. 5.

    Thivel D, Rumbold PL, King NA, Pereira B, Blundell JE, Mathieu ME. Acute post-exercise energy and macronutrient intake in lean and obese youth: a systematic review and meta-analysis. Int J Obes. 2016;40:1469–79.

    CAS  Article  Google Scholar 

  6. 6.

    Beaulieu K, Oustric P, Finlayson G. The impact of physical activity on food reward: review and conceptual synthesis of evidence from observational, acute, and chronic exercise training studies. Curr Obes Rep. 2020;9:63–80.

    Article  Google Scholar 

  7. 7.

    Blundell JE, King NA. Physical activity and regulation of food intake: current evidence. Med Sci Sports Exerc. 1999;31:S573–83.

    CAS  Article  Google Scholar 

  8. 8.

    Blundell JE, Gibbons C, Beaulieu K, Casanova N, Duarte C, Finlayson G, et al. The drive to eat in homo sapiens: energy expenditure drives energy intake. Physiol Behav. 2020;219:112846.

    CAS  Article  Google Scholar 

  9. 9.

    King NA, Burley VJ, Blundell JE. Exercise-induced suppression of appetite: effects on food intake and implications for energy balance. Eur J Clin Nutr. 1994;48:715–24.

    CAS  PubMed  Google Scholar 

  10. 10.

    King NA, Lluch A, Stubbs RJ, Blundell JE. High dose exercise does not increase hunger or energy intake in free living males. Eur J Clin Nutr. 1997;51:478–83.

    CAS  Article  Google Scholar 

  11. 11.

    King JA, Miyashita M, Wasse LK, Stensel DJ. Influence of prolonged treadmill running on appetite, energy intake and circulating concentrations of acylated ghrelin. Appetite 2010;54:492–8.

    CAS  Article  Google Scholar 

  12. 12.

    Green SM, Burley VJ, Blundell JE. Effect of fat- and sucrose-containing foods on the size of eating episodes and energy intake in lean males: potential for causing overconsumption. Eur J Clin Nutr. 1994;48:547–55.

    CAS  PubMed  Google Scholar 

  13. 13.

    Hubert P, King NA, Blundell JE. Uncoupling the effects of energy expenditure and energy intake: appetite response to short-term energy deficit induced by meal omission and physical activity. Appetite 1998;31:9–19.

    CAS  Article  Google Scholar 

  14. 14.

    King JA, Wasse LK, Ewens J, Crystallis K, Emmanuel J, Batterham RL, et al. Differential acylated ghrelin, peptide YY3-36, appetite, and food intake responses to equivalent energy deficits created by exercise and food restriction. J Clin Endocrinol Metab. 2011;96:1114–21.

    CAS  Article  Google Scholar 

  15. 15.

    Borer KT, Wuorinen E, Ku K, Burant C. Appetite responds to changes in meal content, whereas ghrelin, leptin, and insulin track changes in energy availability. J Clin Endocrinol Metab. 2009;94:2290–8.

    CAS  Article  Google Scholar 

  16. 16.

    Alajmi N, Deighton K, King JA, Reischak-Oliveira A, Wasse LK, Jones J, et al. Appetite and energy intake responses to acute energy deficits in females versus males. Med Sci Sports Exerc. 2016;48:412–20.

    CAS  Article  Google Scholar 

  17. 17.

    Thivel D, Finlayson G, Miguet M, Pereira B, Duclos M, Boirie Y, et al. Energy depletion by 24-h fast leads to compensatory appetite responses compared with matched energy depletion by exercise in healthy young males. Br J Nutr. 2018;120:583–92.

    CAS  Article  Google Scholar 

  18. 18.

    Cameron JD, Goldfield GS, Riou ME, Finlayson GS, Blundell JE, Doucet E. Energy depletion by diet or aerobic exercise alone: impact of energy deficit modality on appetite parameters. Am J Clin Nutr. 2016;103:1008–16.

    CAS  Article  Google Scholar 

  19. 19.

    Thivel D, Doucet E, Julian V, Cardenoux C, Boirie Y, Duclos M. Nutritional compensation to exercise- vs. diet-induced acute energy deficit in adolescents with obesity. Physiol Behav. 2017;176:159–64.

    CAS  Article  Google Scholar 

  20. 20.

    Ueda SY, Yoshikawa T, Katsura Y, Usui T, Fujimoto S. Comparable effects of moderate intensity exercise on changes in anorectic gut hormone levels and energy intake to high intensity exercise. J Endocrinol. 2009;203:357–64.

    CAS  Article  Google Scholar 

  21. 21.

    Franz MJ, VanWormer JJ, Crain AL, Boucher JL, Histon T, Caplan W, et al. Weight-loss outcomes: a systematic review and meta-analysis of weight-loss clinical trials with a minimum 1-year follow-up. J Am Diet Assoc. 2007;107:1755–67.

    Article  Google Scholar 

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Acknowledgements

Jams King was supported by the National Institute for Health Research (NIHR) Leicester Biomedical Research Centre. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. David Thivel is supported by the French National University Institute (IUF° throught his 2017–2021 Junior affiliation.

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While DT and JK led the writing of this paper, all the co-authors significantly and equally contributed to this manuscript.

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Correspondence to D. Thivel.

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Thivel, D., Metz, L., Julian, V. et al. Diet- but not exercise-induced iso-energetic deficit induces compensatory appetitive responses. Eur J Clin Nutr 75, 1425–1432 (2021). https://doi.org/10.1038/s41430-020-00853-7

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