Three new meroterpenoids (1–3) together with one known compound (4) were isolated from the culture broth of Perenniporia medulla-panis, a wood-rotting fungus in the family Polyporaceae. Their structures were elucidated by NMR and HRESIMS analyses. These compounds exhibited antioxidant activity with IC50 values ranging from 12.8 to 190.3 μM in the 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical-scavenging assay.
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This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and future Planning (NRF-2016R1A2B2014430). The authors thank Ms Ji-Young Oh, Center for University Research Facility (CURF) at Chonbuk National University, for NMR measurement.