Abstract
The ability to sense saccharides in aqueous media using conventional supramolecular approaches was a turning point in modern chemistry. Herein, we performed oligosaccharide sensing using fluorophore-modified branched glucans. Through the newly developed glucan-based chemosensor, acarbose sensing was achieved in a selectively and sensitive manner. The optical properties and morphological changes in the chemosensor were investigated, revealing that the globule-to-coaggregation process plays a key role in oligosaccharide sensing.
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Acknowledgements
GF acknowledges the generous support provided by Grants-in-Aid (Nos. 19H02746 and 23H04020) from the Japan Society for the Promotion of Science (JSPS). We are grateful to Prof. Yoshihisa Inoue at Osaka University for fruitful discussions.
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Kurohara, H., Hori, Y., Numata, M. et al. Fluorophore-glucan conjugate for oligosaccharide sensing in aqueous media. Polym J 56, 473–480 (2024). https://doi.org/10.1038/s41428-024-00889-7
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DOI: https://doi.org/10.1038/s41428-024-00889-7