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IL-6R blockade by chikusetsusaponin IVa butyl ester inhibits Th17 cell differentiation and ameliorates collagen-induced arthritis

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Acknowledgements

The authors would like to thank Professor Liwei Lu in Hong Kong University for assistance for CIA model establishment and manuscript revision, and Professor  You Yang at East China University of Science and Technology for synthesizing CS. This work was supported by a grant from the National Natural Science Foundation of China (No. 81773973).

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Study conception and design: P.C., J.Y., C.H. Acquisition of data: J.Y., C.Z., Y.L., D.H. Analysis and interpretation of data: J.Y., Y.L., D.H. Paper writing: J.Y. Manuscript editing and revision: P.C., X.S., X.C., J.C.

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Correspondence to Peng Cao.

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The authors declare no competing interests.

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Yang, J., Ling, Y., Hua, D. et al. IL-6R blockade by chikusetsusaponin IVa butyl ester inhibits Th17 cell differentiation and ameliorates collagen-induced arthritis. Cell Mol Immunol (2021). https://doi.org/10.1038/s41423-021-00651-6

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