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References
Lim, J. Z., Ng, N. S. & Thomas, C. Prevention and treatment of diabetic foot ulcers. J. R. Soc. Med. 110, 104–109 (2017).
Pereira, S. G., Moura, J., Carvalho, E. & Empadinhas, N. Microbiota of chronic diabetic wounds: ecology, impact, and potential for innovative treatment strategies. Front. Microbiol. 8, 1791 (2017).
Patel, S., Srivastava, S., Singh, M. R. & Singh, D. Mechanistic insight into diabetic wounds: Pathogenesis, molecular targets and treatment strategies to pace wound healing. Biomed. Pharmacother. 112, 108615 (2019).
Pichu, S., Patel, B. M., Apparsundaram, S. & Goyal, R. K. Role of biomarkers in predicting diabetes complications with special reference to diabetic foot ulcers. Biomark. Med. 11, 377–388 (2017).
Yager, D. R., Kulina, R. A. & Gilman, L. A. Wound fluids: a window into the wound environment? Int. J. Low. Extrem. Wounds 6, 262–272 (2007).
Boykin, J. V. Jr. Wound nitric oxide bioactivity: a promising diagnostic indicator for diabetic foot ulcer management. J. Wound Ostomy Cont. Nurs. 37, 25–32 (2010). quiz3-4.
Moura, J., da Silva, L., Cruz, M. T. & Carvalho, E. Molecular and cellular mechanisms of bone morphogenetic proteins and activins in the skin: potential benefits for wound healing. Arch. Dermatol. Res. 305, 557–569 (2013).
Goodarzi G., Maniati M., Qujeq D. The role of microRNAs in the healing of diabetic ulcers. Int. Wound J. 2019.
Moura J. et al. Impaired T-cell differentiation in diabetic foot ulceration. Cell Mol. Immunol. 14, 758–769 (2016).
Acknowledgements
We acknowledge support from the Sociedade Portuguesa de Diabetologia (SPD): Bolsa Almeida Ruas 2016, FEDER - strategic project COMPETE: POCI-01-0145-FEDER-007440, European Foundation for the Study of Diabetes (EFSD) and HealthyAging2020: CENTRO-01-0145-FEDER-000012N2323.
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Moura, J., Rodrigues, J., Gonçalves, M. et al. Imbalance in T-cell differentiation as a biomarker of chronic diabetic foot ulceration. Cell Mol Immunol 16, 833–834 (2019). https://doi.org/10.1038/s41423-019-0233-1
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DOI: https://doi.org/10.1038/s41423-019-0233-1