Li X, Tian M, Deng Y, She T, Li K. Advantages of Sedation With Remimazolam Compared to Midazolam for the Removal of Impacted Tooth in Patients With Dental Anxiety. J Oral Maxillofac Surg 2023; DOI: 10.1016/j.joms.2023.02.001.

The use of remimazolam results in faster onset, more rapid recovery, and lower incidence of post-operative side effects compared to midazolam.

Patients with dental anxiety and who were to undergo impacted tooth removal were randomised into remimazolam and midazolam groups. The primary variable was the type of sedative, while the primary outcome variables were the onset time, awakening time, recovery time, and post-operative side effects. A total of 83 patients were included, with 42 in the remimazolam group and 41 in the midazolam group. Patients in the remimazolam group had significantly shorter onset time, awakening time, and recovery time compared to those in the midazolam group. Post-operative side effects were more frequent in the midazolam group. Following surgery, the Modified Dental Anxiety Scale scores in both groups were significantly lower than prior to surgery. Satisfaction levels scores for the patients and doctor were higher in the remimazolam group than in the midazolam group.