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Management of amelogenesis imperfecta in an adult patient: a short review and clinical report

Abstract

Objective This clinical report aims to share with general practitioners a conservative approach to treat patients with amelogenesis imperfecta (AI).

Clinical considerations In relatively young patients, a conservative treatment approach is essential in order to maintain the vitality of the teeth and provide successful outcomes. In this clinical report, the diagnoses and treatment plan of an 18-year-old male patient diagnosed with AI is discussed. Composite rehabilitation followed by orthodontic treatment was considered the most conservative treatment approach for this patient.

Conclusion Bonding to well-mineralised enamel can be a predictable and successful treatment approach for young patients diagnosed with AI.

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References

  1. Gadhia K, McDonald S, Arkutu N, Malik K. Amelogenesis imperfecta: an introduction. Br Dent J 2012; 8: 377.

  2. Lau E C, Mohandras T K, Shapiro L J, Slavkin H C, Snead M L. Human and mouse amelogenin gene loci are on the sex chromosomes. Genomics 1989; 4: 162-168.

  3. Lau E C, Slavkin H C, Snead M L. Analysis of human enamel genes insights into genetic disorders of enamel. Cleft Palate J 1990; 27: 121-130.

  4. Collins M A, Mauriello S M, Tyndall D A, Wright J T. Dental anomalies associated with amelogenesis imperfecta: a radiographic assessment. Oral Surg Oral Med Oral pathol Oral Radiol Endod 1999; 3: 358-364.

  5. Wright J T. The molecular etiologies and associated phenotypes of Amelogenesis imperfecta. Am J Med Genet A 2006; 23: 2547-2555.

  6. Sabandal M M, Schäfer E. Amelogenesis imperfecta: review of diagnostic findings and treatment concepts. Odontology 2016; 104: 245-256.

  7. Weinmann J P, Svoboda J F, Woods R W. Hereditary disturbances of enamel formation and calcification. JADA 1945; 32: 397-418.

  8. Witkop Jr C J. Amelogenesis imperfecta, dentinogenesis imperfecta and dentin dysplasia revisited: problems in classification. J Oral Pathol 1988; 17(9-10): 547-553.

  9. Pavlič A, Battelino T, Trebušak Podkrajšek K, Ovsenik M. Craniofacial characteristics and genotypes of amelogenesis imperfecta patients. Eur J Orthod 2011; 33: 325-331.

  10. Hunter L, Stone D. Supraoccluding cobalt-chrome onlays in the management of amelogenesis imperfecta in children: A 2year case report. Quintessence Int 1997; 28: 15-19.

  11. Chan K H, Ho E H, Botelho M G, Pow E H. Rehabilitation of amelogenesis imperfecta using a reorganised approach: A case report. Quintessence Int 2011; 42: 385-391.

  12. Seow W K. Developmental defects of enamel and dentine: challenges for basic science research and clinical management. Aust Dent J. 2014; 59: 143-154.

  13. Horowitz R A, Gautam D K, Karol S, Kumari B. Periodontal management and restoration of an amelogenesis imperfecta patient: a case report. Compend Contin Educ Dent 2014; 35: e6-11.

  14. Koruyucu M, Bayram M, Tuna E B, Gencay K, Seymen F. Clinical findings and long-term managements of patients with amelogenesis imperfecta. Eur J Dent 2014; 8: 546-552.

  15. Nusier M, Yassin O, Hart T C, Samimi A, Wright J T. Phenotypic diversity and revision of the nomenclature for autosomal recessive amelogenesis imperfecta. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2004; 97: 220-230.

  16. Wright J T, Frazier-Bowers S, Simmons D et al. Phenotypic variation in FAM83H-associated amelogenesis imperfecta. J Dent Res 2009; 4: 356-360.

  17. Bäckman B, Holm A K. Amelogenesis imperfecta: prevalence and incidence in a northern Swedish county. Community Dent Oral Epidemiol 1986; 1: 43-47.

  18. Chosack A, Eidelman E, Wisotski I, Cohen T. Amelogenesis imperfecta among Israeli Jews and the description of a new type of local hypoplastic autosomal recessive amelogenesis imperfecta. Oral Surg Oral Med Oral Pathol 1979; 2: 148-156.

  19. Witkop Jr C J. Genetics and dentistry. Eugen Q 1958; 5: 15-21.

  20. Witkop Jr C J. Genetic disease of the oral cavity. In Tiecke R W (ed) Oral Pathology. pp 801-805. New York: McGraw-Hill Book Company, 1965.

  21. Coffield K D, Phillips C, Brady M, Roberts M W, Strauss R P, Wright J T. The psychosocial impact of developmental dental defects in people with hereditary amelogenesis imperfecta. J Am Dent Assoc 2005; 5: 620-630.

  22. Bouvier D, Duprez J P, Pirel C, Vincent B. Amelogenesis imperfecta - a prosthetic rehabilitation: a clinical report. J Prosthet Dent 1999; 2: 130-131.

  23. Patel M, McDonnell S T, Iram S, Chan M F W-Y. Amelogenesis imperfecta - lifelong management. Restorative management of the adult patient. Br Dent J 2013; 9: 449-457.

  24. Borges B C.D, de Vasconselos A A M, Cunha A G.G, Pinheiro F H S L, Machado, C T, dos Santos A J.S. Preliminary Clinical Reports of a Novel Night-Guard Tooth Bleaching Technique Modified by Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP). Eur J Esthet Dent 2011; 6: 446-453.

  25. Özgül B M, Saat S, Sönmez H, Öz F T. Clinical evaluation of desensitizing treatment for incisor teeth affected by molar-incisor hypomineralization. J Clin Pediatr Dent 2013; 38: 101-105.

  26. Kwok-Tung L, King N. The restorative management of amelogenesis imperfecta in the mixed dentition. J Clin Pediatr Dent 2007; 31: 130-135.

  27. Sapir S, Shapira J. Clinical solutions for developmental defects of enamel and dentin in children. Pediatr Dent 2007; 29: 330-336.

  28. Chen C F, Hu J C, Bresciani E, Peters M C, Estrella M R. Treatment considerations for patient with Amelogenesis Imperfecta: a review. Braz Dent Sci 2013; 16: 7-18.

  29. Seow W K, Amaratunge A. The effects of acid-etching on enamel from different clinical variants of amelogenesis imperfecta: an SEM study. Pediatr Dent 1998; 20: 37-42.

  30. Langeland K, Langeland L K. Pulp reactions to crown preparation, impression, temporary crown fixation, and permanent cementation. J Prosthet Dent 1965; 15: 129-143.

  31. Strauch S, Hahnel S. Restorative treatment in patients with Amelogenesis imperfecta: a review. J Prosthodont 2018; 27: 618-623.

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Correspondence to Islam Abd Alraheam.

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Abd Alraheam, I., Donovan, T. Management of amelogenesis imperfecta in an adult patient: a short review and clinical report. Br Dent J 229, 239–243 (2020). https://doi.org/10.1038/s41415-020-1990-z

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