Dentistry and Parkinson's disease: learnings from two case reports


Parkinson's disease is one of the most common conditions affecting the older generation. It is a progressive neurological condition presenting with motor, non-motor and behavioural symptoms that may impact upon oral health. Protecting and maintaining oral health for these individuals is paramount to their comfort, function and quality of life. To do so requires an individualised care plan considering the current stage and progression of their condition, access to care, ability to safely tolerate treatment and oral prostheses, their supporting network, and their own wishes. This paper reviews the current literature on Parkinson's disease and discusses two case reports of patients at differing stages of the condition. It emphasises the importance of a multidisciplinary approach, reasonable adjustments and the use of various techniques and skills within a dentist's armamentarium.

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  1. 1.

    Lebouvier T, Chaumette T, Pailusson S et al. The second brain and Parkinson's disease. Eur J Neurosci 2009; 30: 735-741.

  2. 2.

    Parkinson's UK. The Incidence and Prevalence of Parkinson's in the UK. 2017. Available at (accessed June 2019).

  3. 3.

    World Health Organisation. Neurological Disorders: Public Health Challenges. 2006. Available at (accessed June 2019).

  4. 4.

    Ayano G. Dopamine: Receptors, Functions, Synthesis, Pathways, Locations and Mental Disorders: Review of Literatures. J Ment Disord Treat 2016; 2: 120.

  5. 5.

    Jeter C B, Rozas N S, Sadowsky J M, Jones D J. Parkinson's Disease Oral Health Module: Interprofessional Coordination of Care. MedEdPORTAL 2018; 14: 10699.

  6. 6.

    Lill C M, Roehr J T, McQueen M B. Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. PLoS Genet 2012; 8: e1002548.

  7. 7.

    Tanner C M, Goldman S M. Epidemiology of Parkinson's disease. Neurol Clin 1996; 14: 317-335.

  8. 8.

    Jafari S, Etminan M, Aminzadeh F, Samii A. Head injury and risk of Parkinson disease: a systematic review and meta-analysis. Mov Disord 2013; 28: 1222-1229.

  9. 9.

    Schapira A H. Mitochondrial dysfunction in Parkinson's disease. Cell Death Differ 2007; 14: 1261-1266.

  10. 10.

    National Institute of Neurological Disorders and Stroke. Parkinson's Disease: Hope through Research. What causes the disease? Available at (accessed June 2019).

  11. 11.

    Nagatsu T, Sawada M. Inflammatory process in Parkinson's disease: role for cytokines. Curr Pharm Des 2005; 11: 999-1016.

  12. 12.

    Tansey M, Sulzer D, Standaert D G. Inflammation in Parkinson's disease. 2016. Available at (accessed June 2019).

  13. 13.

    Kaur T, Uppoor A, Naik D. Parkinson's disease and periodontitis the missing link? A review. Gerodontology 2016; 33: 434-438.

  14. 14.

    Chen J J. Parkinson disease: A summary of recent evidence-based medicine reviews. Mental Health Clinician 2012; 2: 25-31.

  15. 15.

    National Institute for Health and Care Excellence. Parkinson's disease in adults: pharmacological management of motor symptoms. 2017. Available at (accessed June 2019).

  16. 16.

    Munchau A, Bhatia K P. Pharmacological Treatment of Parkinson's Disease. BMJ 2000; 76: 602-610.

  17. 17.

    Barker R A. The Trials and Tribulation of Cell Transplants for Parkinson's Disease! 2017. Available at (accessed June 2019).

  18. 18.

    National Institute for Health and Care Excellence. Interventional procedure overview of subthalamotomy for Parkinson's disease. 2004. Available at (accessed June 2019).

  19. 19.

    Filograna R, Beltramini M, Bubacco L, Bisaglia M. Anti-Oxidants in Parkinson's Disease Therapy: A Critical Point of View. Curr Neuropharmacol 2016; 14: 260-271.

  20. 20.

    Mischley L K, Lau R C, Bennett R D. Role of Diet and Nutritional Supplements in Parkinson's Disease Progression. Oxid Med Cell Longev 2017; 6405278. DOI: 10.1155/2017/6405278.

  21. 21.

    Li X, Li W, Liu G, Shen X, Tang Y. Association between cigarette smoking and Parkinson's disease: A meta-analysis. Arch Gerontol Geriatr 2015; 61: 510-516.

  22. 22.

    Parkinson's Foundation. Stages of Parkinson's. Available at (accessed June 2019).

  23. 23.

    Hoehn M M, Yahr M D. Parkinsonism: onset, progression, and mortality. Neurology 1967; 17: 427-442.

  24. 24.

    Schrag A, Dodel R, Spottke A, Bornschein B, Siebert U, Quinn N P. Rate of clinical progression in parkinson's disease. a prospective study. Mov Disord 2007; 22: 938-945.

  25. 25.

    Pretty I A, Ellwood R P, Lo E C et al. The Seattle Care Pathway for securing oral health in older patients. Gerodontology 2014; 31 (Spec Iss): 77-87.

  26. 26.

    Fiske J, Hyland K. Parkinson's disease and oral care. Dent Update 2000; 27: 58-65.

  27. 27.

    Romero-Perez M J, Mang-de la Rosa Mdel R, Lopez-Jimenez J, Fernandes-Feijoo J, Curando-Soriano A. Implants in disabled patients: a review and update. Med Oral Patol Cir Bucal 2014; 19: e478-e482.

  28. 28.

    Packer M E. Are dental implants the answer to tooth loss in patients with Parkinson's disease? Prim Dent J 2015; 4: 35-41.

  29. 29.

    Heckmann S M, Heckmann J G, Weber H P. Clinical outcomes of three Parkinson's disease patients treated with mandibular implant overdentures. Clin Oral Implan Res 2000; 11: 566-571.

  30. 30.

    Deliberador T M, Marengo G, Scaratti R, Giovanini A F, Zielak J C, Baratto Filho F. Accidental aspiration in a patient with Parkinson's disease during implant-supported prostheses construction: A case report. Spec Care Dentist 2011; 31: 156-161.

  31. 31.

    Chu F C, Deng F L, Siu A S, Chow T W. Implant-tissue supported, magnet-retained mandibular overdenture for an edentulous patient with Parkinson's disease: a clinical report. J Prosthet Dent 2004; 91: 219-222.

  32. 32.

    Packer M, Nikitin V, Coward T, David D M, Fiske J. The potential benefits of dental implants on the oral health quality of life of people with Parkinson's disease. Gerodontology 2009; 26: 11-18.

  33. 33.

    Steele J G, Treasure E T, O'Sullivan I, Morris J, Murray J J. Adult Dental Health Survey 2009: transformations in British oral health 1968-2009. Br Dent J 2012; 213: 523-527.

  34. 34.

    Muller T, Palluch R, Jackowski J. Caries and periodontal disease in patients with Parkinson's Disease. Spec Care Dentist 2011; 31: 178-181.

  35. 35.

    Cicciu M, Risitano G, Lo Giudice G, Bramanti E. Periodontal health and caries prevalence evaluation in patients affected by Parkinson's disease. Parkinsons Dis 2012; 541908. DOI: 10.1155/2012/541908.

  36. 36.

    Hanaoka A, Kashihara K. Increased frequency of caries, periodontal disease and tooth loss in patients with Parkinson's disease. J Clin Neurosci 2009; 16: 1279-1282.

  37. 37.

    Wimmer G. Janda M, Wieselmann-Penkner K, Jakse N, Polansky R, Pertl C. Coping with stress: its influence on periodontal disease. J Periodontol 2002; 73: 1343-1351.

  38. 38.

    Tjaden K. Speech and Swallowing in Parkinson's Disease. Top Geriatr Rehabil 2008; 24: 115-126.

  39. 39.

    British Society of Gerodontology. Guidelines for the Oral Healthcare of Stroke Survivors. 2010. Available at (accessed June 2019).

  40. 40.

    American Speech-Language-Hearing Association. Dysarthria: Tips for Talking with Someone Who Has Dysarthria. Available at (accessed June 2019).

  41. 41.

    National Institute of Neurological Disorders and Stroke. Parkinson's Disease: Hope Through Research: How is the disease treated? Available at (accessed June 2019).

  42. 42.

    Verhoeff M C, Lobbezoo F, Wetselaar P, Aarab G, Koutris M. Parkinson's disease, temporomandibular disorders and bruxism: A pilot study. J Oral Rehabil 2018; 45: 854-863.

  43. 43.

    Guaita M, Hogl B. Current treatments of bruxism. Curr Treat Options Neurol 2016; 18: 10.

  44. 44.

    All Wales Special Interest Group. Dysphagia and Oral Health: Recommendations for the Dental Team for the Management of Oral Healthcare of Children and Adults with Dysphagia. 2014. Available at (accessed June 2019).

  45. 45.

    World Gastroenterology Organisation. Dysphagia: Global Guidelines & Cascades. 2014. Available at (accessed June 2019).

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Correspondence to Shazia Kaka.

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Kaka, S., Lane, H. & Sherwin, E. Dentistry and Parkinson's disease: learnings from two case reports. Br Dent J 227, 30–36 (2019).

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