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Monaghan, M. et al. Pediatric Lyme disease: systematic assessment of post-treatment symptoms and quality of life. Pediatr. Res. https://doi.org/10.1038/s41390-023-02577-3 (2023).
Salazar, J. C., Gerber, M. A. & Goff, C. W. Long-term outcome of Lyme disease in children given early treatment. J. Pediatr. 122, 591–593 (1993).
Rose, C. D. et al. Pediatric Lyme arthritis: clinical spectrum and outcome. J. Pediatr. Orthop. 14, 238–241 (1994).
Gerber, M. A., Shapiro, E. D., Burke, G. S., Parcells, V. J. & Bell, G. L. Lyme disease in children in southeastern Connecticut. Pediatric Lyme Disease Study Group. N. Engl. J. Med. 335, 1270–1274 (1996).
Gerber, M. A., Zemel, L. S. & Shapiro, E. D. Lyme arthritis in children: clinical epidemiology and long-term outcomes. Pediatrics 102, 905–908 (1998).
Eppes, S. C. & Childs, J. A. Comparative study of cefuroxime axetil versus amoxicillin in children with early Lyme disease. Pediatrics 109, 1173–1177 (2002).
Thorstrand, C., Belfrage, E., Bennet, R., Malmborg, P. & Eriksson, M. Successful treatment of neuroborreliosis with ten day regimens. Pediatr. Infect. Dis. J. 21, 1142–1145 (2002).
van Samkar, A. et al. Clinical characteristics of Lyme neuroborreliosis in Dutch children and adults. Eur. J. Pediatr. 182, 1183–1189 (2023).
Berglund, J., Stjernberg, L., Ornstein, K., Tykesson-Joelsson, K. & Walter, H. 5-y Follow-up study of patients with neuroborreliosis. Scand. J. Infect. Dis. 34, 421–425 (2002).
Skogman, B. H. et al. Long-term clinical outcome after Lyme neuroborreliosis in childhood. Pediatrics 130, 262–269 (2012).
Fallon, B. A., Madsen, T., Erlangsen, A. & Benros, M. E. Lyme borreliosis and associations with mental disorders and suicidal behavior: a nationwide Danish Cohort Study. Am. J. Psychiatry 178, 921–931 (2021).
Haahr, R. et al. Risk of neurological disorders in patients with European Lyme neuroborreliosis: a nationwide, population-based cohort study. Clin. Infect. Dis. 71, 1511–1516 (2020).
Adams, W. V., Rose, C. D., Eppes, S. C. & Klein, J. D. Long-term cognitive effects of Lyme disease in children. Appl. Neuropsychol. 6, 39–45 (1999).
Vazquez, M., Sparrow, S. S. & Shapiro, E. D. Long-term neuropsychologic and health outcomes of children with facial nerve palsy attributable to Lyme disease. Pediatrics 112, e93–e97 (2003).
This work was supported by the Clinical and Translational Science Institute at Children’s National (CTSI-CN) [Grant numbers UL1TR001876-05 and UL1TR001876-02S1] and the Intramural Research Program of the National Institute of Allergy and Infectious Diseases, National Institutes of Health (to A.M.).
M.M. is currently employed by the National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health. All data for this manuscript were collected prior to her employment at the National Institutes of Health. A.M. is employed by the National Institute of Allergy and Infectious Diseases, National Institutes of Health; A.M. has a patent (US 8,926,989) and serves as an unpaid scientific advisor to the Global Lyme Alliance and the American Lyme Disease Foundation. The other authors declare no competing interests.
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
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Monaghan, M., Norman, S., Gierdalski, M. et al. Reply to Correspondence. Pediatr Res (2023). https://doi.org/10.1038/s41390-023-02790-0