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Anthropometric status of preschoolers and elementary school children with ADHD: preliminary results from the EPINED study

Abstract

Background

A current area of research interest is the association between ADHD and weight status. This paper aimed to describe the anthropometric status of school children with ADHD, considering age and clinical presentation (inattentive, hyperactive-impulsive, or combined), compared with control children.

Methods

Participants came from the “Epidemiological Research Project on Neurodevelopmental Disorders” and consisted of 198 preschoolers (41 with ADHD) and 389 elementary school children (163 with ADHD). ADHD was diagnosed using DSM-5 criteria. Anthropometric measurements were taken at various anatomical points, and height, weight, and body composition were also measured.

Results

In preschoolers, an association was found between hyperactive-impulsive ADHD and greater height and lower waist-to-height ratio. In elementary school children, regardless of the medication, combined ADHD was associated with smaller head, hip, arm, and thigh circumferences and lower weight, height, and BMI. A total of 19.7% of them were underweight. In contrast, children with inattentive and hyperactive/impulsive presentations presented the highest percentage of overweight/obesity (56%).

Conclusion

The anthropometric status of the school children with ADHD showed differences in terms of age and presentation. Preschoolers with hyperactive-impulsive ADHD are taller, and elementary school children with combined ADHD are shorter and smaller than their age-matched control peers.

Impact

  • The anthropometric status of the school children with ADHD showed differences in terms of age and presentation.

  • Preschoolers with hyperactive-impulsive ADHD are taller than their control peers.

  • Elementary school children with combined ADHD, regardless of the pharmacological treatment, are shorter and smaller than their control peers.

  • Medication may anthropometrically affect the height of children with inattentive presentation.

  • Anthropometric and dietary monitoring should be recommended to parents of children with ADHD, with and without medication.

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Fig. 1
Fig. 2: Association between ADHD presentations [control (ref)] and significant anthropometric data in elementary school children.

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Data availability

The datasets generated during and/or analyzed during the current study are available from the corresponding author upon reasonable request.

References

  1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders: DSM-5 (American Psychiatric Association). https://doi.org/10.1176/appi.books.9780890425596.744053 (2013).

  2. Canals Sans, J., Morales Hidalgo, P., Roigé Castellví, J., Voltas Moreso, N. & Hernández Martínez, C. Prevalence and epidemiological characteristics of ADHD in pre-school and school age children in the province of Tarragona, Spain. J. Atten. Disord. 25, 1818–1833 (2021).

    Article  PubMed  Google Scholar 

  3. Sayal, K., Prasad, V., Daley, D., Ford, T. & Coghill, D. ADHD in children and young people: prevalence, care pathways, and service provision. Lancet Psychiatry 5, 175–186 (2018).

    Article  PubMed  Google Scholar 

  4. Pinhas-Hamiel, O. et al. Attention-deficit/hyperactivity disorder and obesity: a national study of 1.1 million Israeli adolescents. J. Clin. Endocrinol. Metab. 107, e1434–e1443 (2022).

    Article  PubMed  Google Scholar 

  5. Jongpitakrat, K. & Limsuwan, N. Prevalences of overweight and obesity in children and adolescents: the comparison of ADHD and other clinical samples. J. Atten. Disord. 26, 1464–1470. https://doi.org/10.1177/10870547221081106 (2022).

  6. Childress, A. C. et al. Long-term treatment with extended-release methylphenidate treatment in children aged 4 to <6. J. Am. Acad. Child Adolesc. Psychiatry 61, 80–92 (2022).

    Article  PubMed  Google Scholar 

  7. Racicka, E., Hanć, T., Giertuga, K., Bryńska, A. & Wolańczyk, T. Prevalence of overweight and obesity in children and adolescents With ADHD: the significance of comorbidities and pharmacotherapy. J. Atten. Disord. 22, 1095–1108 (2018).

    Article  PubMed  Google Scholar 

  8. Goulardins, J. B. et al. The relationship between motor skills, ADHD symptoms, and childhood body weight. Res Dev. Disabil. 55, 279–286 (2016).

    Article  PubMed  Google Scholar 

  9. Ptacek, R., Kuzelova, H., Paclt, I., Zukov, I. & Fischer, S. Anthropometric changes in non-medicated ADHD boys. Neuroendocrinol. Lett. 30, 377–381 (2009).

    PubMed  Google Scholar 

  10. Hanć, T. et al. Attention-deficit/hyperactivity disorder is related to decreased weight in the preschool period and to increased rate of overweight in school-age boys. J. Child Adolesc. Psychopharmacol. 25, 691–700 (2015).

    Article  PubMed  Google Scholar 

  11. Faraone, S. V., Lecendreux, M. & Konofal, E. Growth dysregulation and ADHD: an epidemiologic study of children in France. J. Atten. Disord. 16, 572–578 (2012).

    Article  PubMed  Google Scholar 

  12. Biederman, J., Mick, E. & Faraone, S. V. Age-dependent decline of symptoms of attention deficit hyperactivity disorder: impact of remission definition and symptom type. Am. J. Psychiatry 157, 816–818 (2000).

    Article  CAS  PubMed  Google Scholar 

  13. Turan, S., Tunctürk, M., Çıray, R. O., Halaç, E. & Ermiş, Ç. ADHD and risk of childhood adiposity: a review of recent research. Curr. Nutr. Rep. 10, 30–46 (2021).

    Article  PubMed  Google Scholar 

  14. el Archi, S. et al. Negative affectivity and emotion dysregulation as mediators between ADHD and disordered eating: a systematic review. Nutrients 12, 1–34 (2020).

    Article  Google Scholar 

  15. Dmitrzak-Weglarz, M. et al. Common and unique genetic background between attention-deficit/hyperactivity disorder and excessive body weight. Genes (Basel) 12, 1407 (2021).

    Article  CAS  PubMed  Google Scholar 

  16. Carucci, S. et al. Long term methylphenidate exposure and growth in children and adolescents with ADHD. A systematic review and meta-analysis. Neurosci. Biobehav. Rev. 120, 509–525 (2021).

    Article  CAS  PubMed  Google Scholar 

  17. Schwartz, B. S. et al. Attention deficit disorder, stimulant use, and childhood body mass index trajectory. Pediatrics 133, 668–676 (2014).

    Article  PubMed  PubMed Central  Google Scholar 

  18. Yackobovitch-Gavan, M. et al. Sex-specific long-term height and body mass index trajectories of children diagnosed with attention-deficit/hyperactivity disorder and treated with stimulants. J. Pediatr. 238, 296–304.e4 (2021).

    Article  CAS  PubMed  Google Scholar 

  19. Granato, M. F., Ferraro, A. A., Lellis, D. M. & Casella, E. B. Associations between attention-deficit hyperactivity disorder (ADHD) treatment and patient nutritional status and height. Behav. Neurol. 2018, 1–7 (2018).

    Article  Google Scholar 

  20. Harstad, E. B. et al. ADHD, stimulant treatment, and growth: a longitudinal study. Pediatrics 134, e935–e944 (2014).

    Article  PubMed  PubMed Central  Google Scholar 

  21. Biederman, J. et al. Growth deficits and attention-deficit/hyperactivity disorder revisited: impact of gender, development, and treatment. Pediatrics 111, 1010–1016 (2003).

    Article  PubMed  Google Scholar 

  22. Cerrillo-Urbina, A. J. et al. The effects of physical exercise in children with attention deficit hyperactivity disorder: a systematic review and meta-analysis of randomized control trials. Child Care Health Dev. 41, 779–788 (2015).

    Article  CAS  PubMed  Google Scholar 

  23. Villa-González, R., Villalba-Heredia, L., Crespo, I., del Valle, M. & Olmedillas, H. A systematic review of acute exercise as a coadjuvant treatment of ADHD in young people. Psicothema 32, 67–74 (2020).

    PubMed  Google Scholar 

  24. Rusek, W. et al. Changes in children’s body composition and posture during puberty growth. Children (Basel) 8, 288 (2021).

    PubMed  Google Scholar 

  25. Rojo-Marticella, M. et al. Do children with attention-deficit/hyperactivity disorder follow a different dietary pattern than that of their control peers? Nutrients 14, 1131 (2022).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Zhang, S., Huang, Y., Zaid, M. & Tong, L. ADHD symptoms and obesity in chinese children and adolescents: a longitudinal study with abnormal eating behaviors as moderating factors. J. Atten. Disord. 26, 1452–1463 (2022).

    Article  PubMed  Google Scholar 

  27. Gair, S. L., Brown, H. R., Kang, S., Grabell, A. S. & Harvey, E. A. Early development of comorbidity between symptoms of ADHD and anxiety. Res. Child Adolesc. Psychopathol. 49, 311–323 (2021).

    Article  PubMed  PubMed Central  Google Scholar 

  28. Pervanidou, P. et al. Internalizing and externalizing problems in obese children and adolescents: associations with daily salivary cortisol concentrations. Hormones (Athens) 14, 623–631 (2015).

    PubMed  Google Scholar 

  29. Morales-Hidalgo, P., Voltas-Moreso, N., Hernández-Martínez, C. & Canals-Sans, J. Emotional problems in preschool and school-aged children with neurodevelopmental disorders in Spain: EPINED epidemiological project. Res. Dev. Disabil. 135, 104454 (2023).

    Article  PubMed  Google Scholar 

  30. Esteban-Figuerola, P., Morales-Hidalgo, P., Arija-Val, V. & Canals-Sans, J. Are there anthropometric and body composition differences between children with autism spectrum disorder and children with typical development? Analysis by age and spectrum severity in a school population. Autism 25, 1307–1320 (2021).

    Article  PubMed  Google Scholar 

  31. Yuan, Y. et al. Prevalence of overweight and obesity in children and adolescents with intellectual disabilities in China. J. Intellect. Disabil. Res. 65, 655–665 (2021).

    Article  CAS  PubMed  Google Scholar 

  32. Yang, R., Mao, S., Zhang, S., Li, R. & Zhao, Z. Prevalence of obesity and overweight among Chinese children with attention deficit hyperactivity disorder: a survey in Zhejiang Province, China. BMC Psychiatry 13, 133 (2013).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  33. Zerón-Rugerio, M. F. et al. ADHD subtypes are associated differently with circadian rhythms of motor activity, sleep disturbances, and body mass index in children and adolescents: a case–control study. Eur. Child Adolesc. Psychiatry 30, 1917–1927 (2021).

    Article  PubMed  Google Scholar 

  34. Mayes, S. D. et al. ADHD subtypes and comorbid anxiety, depression, and oppositional-defiant disorder: differences in sleep problems. J. Pediatr. Psychol. 34, 328–337 (2009).

    Article  PubMed  Google Scholar 

  35. Garaulet, M. et al. Fragmentation of daily rhythms associates with obesity and cardiorespiratory fitness in adolescents: The HELENA study. Clin. Nutr. 36, 1558–1566 (2017).

    Article  PubMed  Google Scholar 

  36. Kaufman, J. et al. Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): initial reliability and validity data. J. Am. Acad. Child Adolesc. Psychiatry 36, 980–988 (1997).

    Article  CAS  PubMed  Google Scholar 

  37. Achenbach, T. M., & Rescorla, L. A. Child Behavior Checklist for Ages 6-18. Manual for the ASEBA School-Age Forms & Profiles. Burlington, VT: University of Vermont, Research Center for Children, Youth, & Families. (2001).

  38. Achenbach, T. M. Manual for the Youth Self-Report and 1991 Profile (Department of Psychiatry, University of Vermont, 1991).

  39. Cashin, K. & Oot, L. Guide to Anthropometry: A Practical Tool for Program Planners, Managers, and Implementers. Food and Nutrition Technical Assistance III Project (FANTA)/ FHI 360 https://www.fantaproject.org/sites/default/files/resources/FANTA-Anthropometry-Guide-May2018.pdf (2018).

  40. de Onis, M. et al. Development of a WHO growth reference for school-aged children and adolescents. Bull. World Health Organ 85, 660–667 (2007).

    Article  PubMed  PubMed Central  Google Scholar 

  41. Casadei, K. & Kiel, J. Anthropometric Measurement. StatPearls https://www.ncbi.nlm.nih.gov/books/NBK537315/ (2021).

  42. Bowling, A. B., Tiemeier, H. W., Jaddoe, V. W. V., Barker, E. D. & Jansen, P. W. ADHD symptoms and body composition changes in childhood: a longitudinal study evaluating directionality of associations. Pediatr. Obes. 13, 567–575 (2018).

    Article  CAS  PubMed  Google Scholar 

  43. Kesztyüs, D., Lampl, J. & Kesztyüs, T. The weight problem: overview of the most common concepts for body mass and fat distribution and critical consideration of their usefulness for risk assessment and practice. Int. J. Environ. Res. Public Health 18, 11070 (2021).

    Article  PubMed  PubMed Central  Google Scholar 

  44. Macek, P. et al. Optimal body fat percentage cut-off values in predicting the obesity-related cardiovascular risk factors: a cross-sectional cohort study. Diabetes Metab. Syndr. Obes. 13, 1587 (2020).

    Article  PubMed  PubMed Central  Google Scholar 

  45. Wang, Y. & Chen, H. Use of percentiles and scores in anthropometry. In: Preedy, V. R. Editor. Handbook of Anthropometry: Physical Measures of Human Form in Health and Disease. 29–48 (Springer, New York, NY). https://doi.org/10.1007/978-1-4419-1788-1_2 (2012).

  46. Norte-Navarro, A. & Ortiz-Moncada, R. Calidad de la dieta española según el índice de alimentación saludable. Nutr. Hosp. 26, 330–336 (2011).

    CAS  PubMed  Google Scholar 

  47. Hollingshead, A. B. Four factor index of social status. Yale J. Sociol. 8, 21–52 (1975).

    Google Scholar 

  48. Hanć, T. & Cortese, S. Attention deficit/hyperactivity-disorder and obesity: a review and model of current hypotheses explaining their comorbidity. Neurosci. Biobehav. Rev. 92, 16–28 (2018).

    Article  PubMed  Google Scholar 

  49. Seymour, K. E., Reinblatt, S. P., Benson, L. & Carnell, S. Overlapping neurobehavioral circuits in ADHD, obesity, and binge eating: evidence from Neuroimaging Research. CNS Spectr. 20, 401 (2015).

    Article  PubMed  PubMed Central  Google Scholar 

  50. García Solano, M. et al. Weight status in the 6- to 9-year-old school population in Spain: results of the ALADINO 2019 Study. Nutr. Hosp. 38, 943–953 (2021).

    PubMed  Google Scholar 

  51. Swanson, J. et al. Stimulant-related reductions of growth rates in the PATS. J. Am. Acad. Child Adolesc. Psychiatry 45, 1304–1313 (2006).

    Article  PubMed  Google Scholar 

  52. Canals, J., Morales-Hidalgo, P., Jané, M. C. & Domènech, E. ADHD prevalence in Spanish preschoolers: comorbidity, socio-demographic factors, and functional consequences. J. Atten. Disord. 22, 143–153 (2018).

    Article  PubMed  Google Scholar 

  53. Deng, L. et al. Methylphenidate and atomoxetine treatment negatively affect physical growth indexes of school-age children and adolescents with attention-deficit/hyperactivity disorder. Pharm. Biochem Behav. 208, 173225 (2021).

    Article  CAS  Google Scholar 

  54. Biederman, J., Spencer, T. J., Monuteaux, M. C. & Faraone, S. V. A naturalistic 10-year prospective study of height and weight in children with attention-deficit hyperactivity disorder grown up: sex and treatment effects. J. Pediatr. 157, 635–640.e1 (2010).

    Article  PubMed  PubMed Central  Google Scholar 

  55. Hanć, T. & Cieślik, J. Growth in stimulant-naive children with attention-deficit/hyperactivity disorder using cross-sectional and longitudinal approaches. Pediatrics 121, e967–e974 (2008).

    Article  PubMed  Google Scholar 

  56. Aparicio, E., Canals, J., Voltas, N., Valenzano, A. & Arija, V. Emotional symptoms and dietary patterns in early adolescence: a school-based follow-up study. J. Nutr. Educ. Behav. 49, 405–414.e1 (2017).

    Article  PubMed  Google Scholar 

  57. Kaisari, P., Dourish, C. T., Rotshtein, P. & Higgs, S. Associations between core symptoms of attention deficit hyperactivity disorder and both binge and restrictive eating. Front. Psychiatry 9, 103 (2018).

    Article  PubMed  PubMed Central  Google Scholar 

  58. Aparicio, E., Canals, J., Arija, V., De Henauw, S. & Michels, N. The role of emotion regulation in childhood obesity: implications for prevention and treatment. Nutr. Res. Rev. 29, 17–29 (2016).

    Article  CAS  PubMed  Google Scholar 

  59. Sares-Jäske, L., Grönqvist, A., Mäki, P., Tolonen, H. & Laatikainen, T. Family socioeconomic status and childhood adiposity in Europe – a scoping review. Prev. Med. 160, 107095 (2022).

    Article  PubMed  Google Scholar 

  60. Nemet, D., Ben-Zaken, S., Eliakim, R. A. & Eliakim, A. Reduced exercise-induced growth hormone secretion among children with attention-deficit hyperactivity disorder. Growth Horm. IGF Res. 65, 101485 (2022).

    Article  CAS  PubMed  Google Scholar 

  61. Sung, V., Hiscock, H., Sciberras, E. & Efron, D. Sleep problems in children with attention-deficit/hyperactivity disorder: prevalence and the effect on the child and family. Arch. Pediatr. Adolesc. Med. 162, 336–342 (2008).

    Article  PubMed  Google Scholar 

  62. Shen, L.-X. et al. Nutritional complexity in children with ADHD related morbidities in China: a cross-sectional study. Asia Pac. J. Clin. Nutr. 31, 108–117 (2022).

    PubMed  Google Scholar 

  63. Mayes, S. D., Puzino, K., DiGiovanni, C. & Calhoun, S. L. Cross-sectional age analysis of sleep problems in 2 to 17 year olds with ADHD combined, ADHD inattentive, or autism. J. Clin. Psychol. Med. Settings 29, 239–248. https://doi.org/10.1007/S10880-021-09799-9/FIGURES/1 (2022).

  64. Ironside, S., Davidson, F. & Corkum, P. Circadian motor activity affected by stimulant medication in children with attention-deficit/hyperactivity disorder. J. Sleep. Res. 19, 546–551 (2010).

    Article  PubMed  Google Scholar 

  65. Kim, E. et al. Relationship among attention-deficit hyperactivity disorder, dietary behaviours and obesity. Child Care Health Dev. 40, 698–705 (2014).

    Article  CAS  PubMed  Google Scholar 

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Acknowledgements

We thank the Universitat Rovira i Virgili’s Martí Franqués Grant 2020PMF-PIPF-36 and our colleagues Lucía Iglesias-Vázquez and Andrés Díaz-López for their invaluable help. The authors are grateful to the URV English Service for reviewing the manuscript.

Funding

This work was supported by the Ministry of Economy and Competitiveness of Spain and the European Regional Development Fund (ERDF) under Grant PSI2015–64837-P and RTI2018–097124-B-I00.

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Conceptualization: J.C.-S. and V.A.; methodology: J.C.-S. and V.A.; formal analysis: M.R.-M. and V.A.; investigation: P.M.-H., P.E.-F., N.V.-M., and J.C.-S.; data curation: M.R.-M., P.M.-H., N.V.-M., P.E.-F., and J.C.-S.; writing—original draft preparation: M.R.-M., V.A., and J.C.-S.; writing—review and editing: M.R.-M., V.A., P.M.-H, N.V.-M., and J.C.-S.; funding acquisition: J.C.-S. All authors have read and agreed to the published version of the manuscript.

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Correspondence to Josefa Canals-Sans.

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Rojo-Marticella, M., Arija, V., Morales-Hidalgo, P. et al. Anthropometric status of preschoolers and elementary school children with ADHD: preliminary results from the EPINED study. Pediatr Res 94, 1570–1578 (2023). https://doi.org/10.1038/s41390-023-02671-6

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