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Neonatal hypoglycemia: pre-emptive monitoring and treatment may result in normal neurodevelopmental outcome

Pediatric Research (2023)Cite this article

In this issue, Kennedy et al.1 report on caudate volumes and neurodevelopmental outcomes at 9–10 years of age in the “Children with hypoglycemia and their later development” (CHYLD) study in children with and without a history of neonatal hypoglycemia. Smaller caudate volume in this cohort is reported to be associated with greater parent-reported emotional and behavioral difficulties, and poorer prosocial behavior. However, neonatal hypoglycemia was not found to be a mediator in this relationship, except in the case of visual memory, where only those children without neonatal hypoglycemia showed significant associations with caudate volume. Children with neonatal hypoglycemia did not show significant associations between caudate volume and visual memory outcomes.

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  1. Department of Paediatrics, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada

    Emily W. Y. Tam

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  1. Emily W. Y. Tam
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E.W.Y.T. is the sole author of this manuscript, including drafting, and final approval.

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Correspondence to Emily W. Y. Tam.

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Tam, E.W.Y. Neonatal hypoglycemia: pre-emptive monitoring and treatment may result in normal neurodevelopmental outcome. Pediatr Res (2023). https://doi.org/10.1038/s41390-023-02511-7

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