Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Research and training in autism spectrum disorder to catalyze the next genomic and neuroscience revolutions

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.


All prices are NET prices.

Fig. 1: The 2019 Banbury Course on Autism Spectrum Disorders at Cold Spring Harbor Laboratory.


  1. 1.

    Maenner MJ, Shaw KA, Baio J, EdS, Washington A, Patrick M, et al. Prevalence of autism spectrum disorder among children aged 8 years—Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2016. MMWR Surveill Summ. 2020;69:1–12.

    Article  Google Scholar 

  2. 2.

    Lord C, Brugha TS, Charman T, Cusack J, Dumas G, Frazier T, et al. Autism spectrum disorder. Nat Rev Dis Prim. 2020;6:5.

    Article  Google Scholar 

  3. 3.

    Szatmari P, Chawarska K, Dawson G, Georgiades S, Landa R, Lord C, et al. Prospective longitudinal studies of infant siblings of children with autism: lessons learned and future directions. J Am Acad Child Adolesc Psychiatry. 2016;55:179–87.

    Article  Google Scholar 

  4. 4.

    Sebat J, Lakshmi B, Malhotra D, Troge J, Lese-Martin C, Walsh T, et al. Strong association of de novo copy number mutations with autism. Science. 2007;316:445–9.

    CAS  Article  Google Scholar 

  5. 5.

    Satterstrom FK, Kosmicki JA, Wang J, Breen MS, De Rubeis S, An JY, et al. Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism. Cell. 2020;180:568–584 e523.

    CAS  Article  Google Scholar 

  6. 6.

    Sandin S, Schendel D, Magnusson P, Hultman C, Suren P, Susser E, et al. Autism risk associated with parental age and with increasing difference in age between the parents. Mol Psychiatry. 2016;21:693–700.

    CAS  Article  Google Scholar 

  7. 7.

    Conde-Agudelo A, Rosas-Bermudez A, Norton MH. Birth spacing and risk of autism and other neurodevelopmental disabilities: a systematic review. Pediatrics. 2016;137:e20153482.

    Article  Google Scholar 

  8. 8.

    Modabbernia A, Velthorst E, Reichenberg A. Environmental risk factors for autism: an evidence-based review of systematic reviews and meta-analyses. Mol autism. 2017;8:13.

    Article  Google Scholar 

  9. 9.

    Kwon CH, Luikart BW, Powell CM, Zhou J, Matheny SA, Zhang W, et al. Pten regulates neuronal arborization and social interaction in mice. Neuron. 2006;50:377–88.

    CAS  Article  Google Scholar 

  10. 10.

    Sanders SJ, Sahin M, Hostyk J, Thurm A, Jacquemont S, Avillach P, et al. A framework for the investigation of rare genetic disorders in neuropsychiatry. Nat Med. 2019;25:1477–87.

    CAS  Article  Google Scholar 

  11. 11.

    Pasca SP. The rise of three-dimensional human brain cultures. Nature. 2018;553:437–45.

    CAS  Article  Google Scholar 

  12. 12.

    Parikshak NN, Gandal MJ, Geschwind DH. Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders. Nat Rev Genet. 2015;16:441–58.

    CAS  Article  Google Scholar 

  13. 13.

    Berry-Kravis EM, Lindemann L, Jonch AE, Apostol G, Bear MF, Carpenter RL, et al. Drug development for neurodevelopmental disorders: lessons learned from fragile X syndrome. Nat Rev Drug Discov. 2018;17:280–99.

    CAS  Article  Google Scholar 

Download references


Cold Spring Harbor Laboratory and the Nancy Lurie Marks Family Foundation for supporting the workshop.

Author information



Corresponding author

Correspondence to Sergiu P. Paşca.

Ethics declarations

Conflict of interest

JCM has received funding from Janssen Research and Development, receives book royalties from Guilford, Springer, and Lambert Press, and is a consultant with Blackthorn Therapeutics. JV has served on Advisory Boards for Roche, Novartis, and SynapDx. He has received research funding from Roche, Novartis, SynapDx, Seaside Therapeutics, and Forest. He has received editorial stipends from Springer and Wiley. SPP has been consulting for Stem Cell Technologies.

Additional information

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Paşca, S.P., Veenstra-VanderWeele, J. & McPartland, J.C. Research and training in autism spectrum disorder to catalyze the next genomic and neuroscience revolutions. Mol Psychiatry (2020).

Download citation

Further reading


Quick links