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Clinical and immunophenotypic characteristics of familial leukemia predisposition caused by PAX5 germline variants

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Fig. 1: Genetic and immunophenotypic features of the families.


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AE and BP have been supported by CRIS Foundation to Beat Cancer MT was supported by Grants-in-Aid for Scientific Research 19H03614, and AMED 20ck0106467h0002. JH was supported by ERC Stg “PreventALL” 852222. This publication is based upon work from COST Action (CA16223; Working Group 3), supported by COST (European Cooperation in Science and Technology;

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AE, MT, and JH conceived and designed the experiments; MT, FA, UAF, and LY performed molecular and cytogenetic analyses; SM and KI performed and analyzed immunological studies; AO, BP, MV, PS, SE, AB, and AP-M provided samples and clinical data; and AE, MT, FA, and JH wrote the manuscript with feedback from all authors.

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Correspondence to Masatoshi Takagi or Julia Hauer.

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Escudero, A., Takagi, M., Auer, F. et al. Clinical and immunophenotypic characteristics of familial leukemia predisposition caused by PAX5 germline variants. Leukemia (2022).

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