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Intravitreal bevacizumab injection for retinopathy of prematurity and pulmonary hypertension

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Fig. 1: Illustration descripting the potential mechanism by which bevacizumab may exacerbate pulmonary hypertension.

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The data presented in this study are available in this article.


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The authors would like to thank the funding sources. This work was supported in part by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 5 R01 HD072929 09 (SL), Children’s Miracle Network Grant at UC Davis Children’s Hospital (DS).

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Authors and Affiliations



LP drafted the initial manuscript. LP, LD, SL, and DS contributed to the concept, design, reviewed, and revised the manuscript. All the authors have critically revised and approved the final version of the manuscript. All authors agree to be accountable for all aspects of the work.

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Correspondence to Deepika Sankaran.

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The authors declare no competing interests.

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Supplementary information

Supplement Table 1: Description of characteristics among infants treated with intravitreal bevacizumab for ROP.


Supplement Table 2: Description of echocardiographic features, respiratory support, and pulmonary vasodilator therapy before and after intravitreal bevacizumab treatment for ROP.

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Park, L., Donohue, L., Lakshminrusimha, S. et al. Intravitreal bevacizumab injection for retinopathy of prematurity and pulmonary hypertension. J Perinatol (2022).

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