To evaluate perinatal and long-term cardiovascular and respiratory morbidities of children born with nuchal cord.
A large population-based cohort analysis of singleton deliveries was conducted. Maternal and birth characteristics, as well as cardiovascular and respiratory morbidity incidence were evaluated. Kaplan–Meier survival curves were used to compare cumulative hospitalization incidence between groups. Cox regression models were used to control for possible confounders and follow-up length.
243,682 deliveries were included. Of them, 34,332 (14.1%) were diagnosed with nuchal cord. Perinatal mortality rate was comparable between groups (0.5 vs. 0.6%, p = 0.16). Kaplan–Meier survival curves demonstrated no significant differences in cumulative cardiovascular or respiratory morbidity incidence between groups (log rank p = 0.69 and p = 0.10, respectively). Cox regression models reaffirmed a comparable risk for hospitalization between groups (aHR = 0.99 (95% CI 0.85–1.14, p = 0.87) and aHR = 0.97 (95% CI 0.92–1.02, p = 0.28).
Nuchal cord is not associated with higher rate of perinatal mortality nor long-term cardiorespiratory morbidity.
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RM wrote the first draft of the paper. No honorarium, grant, or other form of payment was given to anyone to produce the paper. This study was conducted as part of the requirements for graduation from the Medical School of the Faculty of Health Sciences, Ben-Gurion University of the Negev, Israel.
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Masad, R., Gutvirtz, G., Wainstock, T. et al. The effect of nuchal cord on perinatal mortality and long-term offspring morbidity. J Perinatol 40, 439–444 (2020). https://doi.org/10.1038/s41372-019-0511-x