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The Global Ambulatory Blood Pressure Monitoring (ABPM) in Heart Failure with Preserved Ejection Fraction (HFpEF) Registry. Rationale, design and objectives

Journal of Human Hypertension volume 35, pages 1029–1037 (2021)Cite this article

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Abstract

Hypertension is a major risk factor for the development of heart failure with preserved ejection fraction (HFPEF) and blood pressure (BP) in itself is an important marker of prognosis. The association of BP levels, and hemodynamic parameters, measured by ambulatory blood pressure monitoring (ABPM), with outcomes, in patients with HFPEF is largely unknown. Patients with HFPEF have a substantial burden of co-morbidities and frailty. In addition there are marked geographic differences in HFPEF around the world. How these difference influence the association between BP and outcomes in HFPEF are unknown. The Global Ambulatory Blood Pressure Monitoring (ABPM) in Heart Failure with Preserved Ejection Fraction (HFpEF) Registry aims to assess the relevance of BP parameters, measured by ABPM, on the outcome of HFPEF patients worldwide. Additionally, the influence of other relevant factors such as frailty and co-morbidities will be assessed. Stable HFPEF patients with a previous hospitalization, will be included. Patients should be clinically and hemodynamically stable for at least 4 weeks before study inclusion. Specific data related to HF, biochemical markers, ECG and echocardiography will be collected. An ABPM and geriatric and frailty evaluation will be performed and the association with morbidity and mortality assessed. Follow up will be at least one year.

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Fig. 1: First visit and baseline examination and investigations.
Fig. 2: Follow up visits and assessments.

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Funding

This study is funded by The University of Barcelona.

Author information

Authors and Affiliations

  1. Hospital Clinic. Hypertension and Vascular Risk Unit. University of Barcelona Spain, Barcelona, Spain

    Miguel Camafort-Babkowski & Antonio Coca

  2. Department of Cardiology, Ladoke Akintola University of Technology Nigeria, Ogbomosho, Nigeria

    Akintunde Adeseye

  3. Eduardo Mondlane University Faculty of Medicine Maputo Mozambique, San Diego, CA, USA

    Albertino Damasceno

  4. Federico II University Hospital Naples Italia, Naples, Italy

    Giovanni De Simone

  5. University Emergency Hospital Bucharest Romania, Bucharest, Romania

    Maria Dorobantu

  6. BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK

    Pardeep S. Jhund & Sandosh Padmanabahn

  7. Jichi Medical University School of Medicine Graduate School of Medicine. Tochigi Japan, Shimotsuke, Japan

    Kazuomi Kario & Takahiro Komori

  8. Seoul National University College of Medicine Department of Internal Medicine, Seoul, South Korea

    Hae young Lee

  9. Foscal Clinic. Masira Institute, University of Santander, Bucaramanga, Colombia

    Patricio López-Jaramillo

  10. University College Hospital Ibadan, Ibadan, Nigeria

    Okechukwu Ogah

  11. Virgen de la Arrixaca University Hospital Cardiology Service, Murcia, Spain

    Domingo A. Pascual-Figal

  12. Ewha Women’s University College of Medicine and Graduate School of Medicine. Department of Internal Medicine, Seoul, South Korea

    Wook Bum Pyun

  13. National University of Cuyo Faculty of Medical Sciences, Mendoza, Argentina

    Nicolás Federico Renna

  14. Federal University of Goias Faculty of Medicine, Goianîa, Brazil

    Weimar Kunz Sebba Barroso

  15. Centro De Especialidades Medicas Romana, La Romana, República Dominicana

    Osiris Valdez-Tiburcio

  16. Servicios y Tecnología Cardiovascular de Guatemala. Cardiosolutions, Guatemala City, Guatemala

    Fernando Stuardo Wyss-Quintana

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  1. Miguel Camafort-Babkowski
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  2. Akintunde Adeseye
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Correspondence to Miguel Camafort-Babkowski.

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Camafort-Babkowski, M., Adeseye, A., Coca, A. et al. The Global Ambulatory Blood Pressure Monitoring (ABPM) in Heart Failure with Preserved Ejection Fraction (HFpEF) Registry. Rationale, design and objectives. J Hum Hypertens 35, 1029–1037 (2021). https://doi.org/10.1038/s41371-020-00446-8

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