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Association between microinfarcts and blood pressure trajectories

Journal of Human Hypertension volume 32, page 386 (2018)Cite this article

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To the Editor:

Graff-Radford et al. [1] investigated the association between cerebral microinfarcts and blood pressure (BP) trajectories in 297 elderly individuals who underwent autopsy and had antemortem BP measurements. The authors concluded that there was an association between declining BP in older adults and the presence of subcortical microinfarcts at autopsy. Although, the authors acknowledged that the cause and effect between declining BP and the presence of subcortical microinfarcts remain unclear, the authors hold a view that the observed subcortical microinfarcts may be contributed by declining BP in older age in the Key Points section and the Discussion section. However, this view was not supported be the data in the study. It is not only because the design of the study cannot confirm a cause and effect relation, but mostly because the observed microinfarcts may develop in early old age or even in young adulthood.

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References

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  1. Department of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China

    Peng-Peng Niu

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  1. Peng-Peng Niu
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Correspondence to Peng-Peng Niu.

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Niu, PP. Association between microinfarcts and blood pressure trajectories. J Hum Hypertens 32, 386 (2018). https://doi.org/10.1038/s41371-018-0054-1

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