Abstract
Background: Survival following major surgery in early infancy is over 97% in Australia. This has focussed attention on the long term outcomes for these infants. Although there are many studies regarding developmental outcome of babies who have undergone cardiac surgery, the outcomes for babies who undergo other types of major surgery have been neglected. Unlike their preterm counterparts, infants who undergo major surgery are not routinely enrolled in newborn developmental follow-up clinics.
Objective: To compare the early developmental outcome of infants who underwent cardiac surgery with those who underwent major non-cardiac surgery and healthy controls.
Method: This prospective population-based study enrolled 784 infants between August 2006 and December 2008 from the three Children's Hospitals in New South Wales and their co-located maternity units. They were assessed at one year of age (corrected) using the five subscales (cognition, expressive and receptive language, gross and fine motor) of the Bayley Scales of Infants and Toddler Development (Version-III).
Results: Infants who underwent cardiac surgery scored significantly lower on all subscales than control infants (p< 0.001). Similarly, infants who underwent non-cardiac surgery also scored lower than the control infants on all subscales (p< 0.05). Infants who underwent cardiac surgery scored significantly lower than the infants who underwent non-cardiac surgery on four of the subscales (p<.05). Conclusion: These important early findings suggest that Infants who undergo non-cardiac major surgery and cardiac surgery are at high risk of developmental impairment. Infants who undergo major surgery warrant systematic neurodevelopmental follow-up to determine their long term outcomes.
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Walker, K., Halliday, R., Holland, A. et al. 143 Should Infants Who Have Early Major Surgery Be Enrolled in Follow-Up Clinics?. Pediatr Res 68 (Suppl 1), 75–76 (2010). https://doi.org/10.1203/00006450-201011001-00143
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DOI: https://doi.org/10.1203/00006450-201011001-00143
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