Abstract
Aims: Neuro-psychomotor development follows different evolutionary phases that successive one another with different phases in each child. The achievement of a normal psycho-intellectual development is the main goal of the treatment of Congenital hypothyroidism(CH).
The objective of our study was to evaluate the neuro-psychomotor development and intellectual ability in a group of 127 (74F, 53M) children with permanent CH.
Methods: CH children have carried out: 62.2% assessment of Global Functioning, with analysis of functional acquisitions; 34.6% test with Brunet- Lezine test in order to evaluate the quotient of motor skills, correlated to chronological age; 33.8% a proper reagent Level for assessing the standard of their Intellectual.
Results: 7,6% of children that had assessment of Global Functioning showed an initial slowing of the neuro-muscular development that was confirmed in 2.5% of this children. To the children that had valuation with Brunet-Lezine test 2.3% had moderate delay and 2.3% mild delay; this date was confirmed in 2.3% of children. 4.6% of children had mild delay at the valuation with reactive intellectual level, confirmed in all children. There was no difference between genders.
Conclusions: Most of our patients presented psychomotor and intellectual development in the normal range, only 7.8% of CH children had initial inadequate levels of development (mild or moderate) that was confirmed, at follow-up, only in 3.9% of children, all mild delay. These data represent the clear advantage given by early diagnosis and subsequent therapy in children with CH, which ensures complete somatic and neuropsychic- motor development of the children with this endocrine disorder.
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Baserga, M., Talarico, V., Miniaci, S. et al. 1099 Neuro-Psychomotor Development in Children with Congenital Hypothyroidism. Pediatr Res 68 (Suppl 1), 545 (2010). https://doi.org/10.1203/00006450-201011001-01099
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DOI: https://doi.org/10.1203/00006450-201011001-01099