Abstract
Objective To acquire the situation of pathogeresis, diagnosisand treatment of Kawasaki disease in Shannxi Province. Methods we had a retrospective clinical study on children with KD in six hospital in Xi'an between 1998 and 1999. This is a consecutive study based on the epidemic study on KD of Sino-Japanese between 1993 and 1997. The evaluation include age, sex, season, clinical symptoms and signs, the counting of thrombocyte, ESR, cardiac enzyme series. With the dose of IVGG, all the patients were designed into four groups: A 300∼400mg/kg/d; B 400∼800mg/kg/d; C 1000mg/kg/d; D 2000mg/kg/d, together with aspirin and anticoagulant. Results Sex: male 73; female 31. Age: 1 year 24.03%; 1∼3 years 50.4%; 3∼7 years 22.11%; 7∼14 years 2.88%. 80.76% patients had fever persisting for fine days or more; 82.69%, changes in the extremities; 74.03%, polymorphous exanthema; 78.84%, changes in the lips and oral cavity; 74.63%, nonpurulent cervical lymphalenopathy. There were 21 patients to be diagnosed as acute upper respiratory infection (AURI) by impression; 14, herpangina; 5, cervical lymphadenopathy; 2, lymphomas; 1, thrombocythemia. Conclusion According to recent study, the cardiovascular damage of KD was gradually increased, especially in coronal artery and became the main cause of acquired heart disease in Chinese children with KD. IVGG has been an effective therapy for KD in recent years, using in 400mg/kg/d for 4∼5days was superior to 100∼200mg/kg/d in China.
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Jiao, FY., Pan, KL., Li, ZK. et al. Clinical Study of 104 Cases with Kawasaki Disease. Pediatr Res 53, 176 (2003). https://doi.org/10.1203/00006450-200301000-00133
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DOI: https://doi.org/10.1203/00006450-200301000-00133