In this study, 14 children with G-6-PD deficiency aged 5 to 20 years and 14 healthy controls of the same age group were studied. Erythrocytic G-6-PD(quantitative and qualitatively), erythrocytic GSH-Px (quantitatively) and erythrocytic GSH-Rx activities (qualitatively) and serum vitamin E levels(with HPLC) have been determined.
G-6-PD activity was found to be 2.84±0.91 U/g Hb in the G-6-PD deficient group and 9.32±3.40 U/g Hb in the control group(p<0.05).
Mean serum vit E level was 5.34±0.99 μg/mL in the G-6-PD deficient group and 7.11±1.67 μg/mL in the healthy controls(p<0.05).
Erythrocytic GSH-Px activity was 3.24±0.90 U/g Hb in the G-6-PD deficient cases and 9.09±2.35 U/g Hb in the controls.
GSH-Rx activity was below normal in all G-6-PD deficient cases; in contrary, GSH-Rx was normal in controls.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
öztürk, S., Kilinç, Y., Tanyeli, A. et al. GLUTATHONE PEROXIDASE, GLUTATHINE REDUCTASE AND VITAMIN E LEVELS IN GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY 129. Pediatr Res 41, 771 (1997). https://doi.org/10.1203/00006450-199705000-00148
Issue Date:
DOI: https://doi.org/10.1203/00006450-199705000-00148
