Abstract
Department of Pediatrics. State University Hospital. Rigshospitalet. Copenhagen. Measurement of lung function during tidal breathing in young awake children can be accomplished by the forced oscillation technique (Rosel) and the interrupter technique (Rint). Measurements were compared to forced expiratory volumen (FEV1) and whole body plethysmography (Raw) in 21 asthmatic children aged 4-6 years (median age 5, 9 years) for each dose during metacholine provocation. Transcutaneous oxygen tension was monitored continuosly. For each method measurements are expressed as an index: % change from baseline/coefficient of variation. The sensitivity is expressed as the median provocative dose causing a change from baseline equal to: 2 x the coefficient of variation (PD2cv).
Conclusion: In awake young children Roscl (reactance at 5 Hz), Rint and TcO2 correlate well with Raw during metacholine provocation and have a comparable sensitivity, except for Rint which has a significantly lower sensitivity.
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Klug, B., Bisgaard, H. 284 NON-INVASIVE LUNG FUNCTION TESTING DURING TIDAL BREATHING IN AWAKE YOUNG CHILDREN WITH ASTHMA. Pediatr Res 36, 50 (1994). https://doi.org/10.1203/00006450-199407000-00284
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DOI: https://doi.org/10.1203/00006450-199407000-00284