Abstract
Forty children affected by IDDM with HbAlc<9% have been enrolled. Inclusion criteria were: absence of fluoroangiographic signs of diabetic retinopathy, age>10 years, duration of disease>5 years, albumin excretion rate<20 mcg/min. At the beginning of the study all subjects underwent fluoroangiography, monocular colour vision examination (Farnsworth 100 HUE) and glycated haemoglobin. After 4 years the same study protocol has been performed. During the follow-up 18 patients (group A) showed poor metabolic control (mean HbAlc 12.2%) and 22 patients (group B) had good metabolic control (mean HbAlc 8.1%). Colour vision examination as Total Error Score (TES) at the beginning of the study was 63.95(±40.17)in the group B and 68.60(±37.05) in the group A. After 4 years TES was 57.67(±34.56) in group B and 85.67(±42.95) in group A. In patients with HbAlc>9% we observed a significant worsening of chromatic sense(p=0.005) at the end of follow-up. Our study suggests that poor metabolic control can be a risk factor for the impairment of colour vision.
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Lobefalo, L., Verrotti, A., Mastropasqua, L. et al. 132 RELATIONSHIP BETWEEN CHROMATIC SENSE AND METABOLIC CONTROL IN DIABETIC CHILDREN: A LONGITUDINAL STUDY. Pediatr Res 36, 24 (1994). https://doi.org/10.1203/00006450-199407000-00132
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DOI: https://doi.org/10.1203/00006450-199407000-00132