Abstract
Immaturity of cardiorespiratory control in preterm infants has been related to inefficient feeding behaviour. We used NIRS to assess whether these infants become hypoxic during feeding. According to their drinking efficiency 21 preterm infants with a gestational age of 33-38 weeks, have been considered to be good or bad drinkers. The latter (N=12) showed an overall decrease in oxygen saturation (Sat), whereas in the good drinkers (N=9) no singificant changes in Sat was found Results: Sign Test:significant ++, not signif. --)
In the bad drinkers the total haemoglobin volume (HbVol), the sum of oxygenated (HbO2) and reduced haemoglobin (Hbred), increased in 10 of 12 newborns. This increment was due to a consistent raise in HbO2, that we did not expect in peripheral deoxigenation. Cytochrome aa3 (Cyt aa3), an index of intracellular O2 availability did not change significantly.
Conclusion: in spite of peripheral hypoxia, preterms considered to be bad drinkers do not have signs of central hypoxia. They seem to have adequate autoregulation to maintain sufficient O2 supply to the brain.
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Von Siebenthai, K., Jonkers, I., Daniels, H. et al. COMPARISON BETWEEN PERIPHERAL AND CENTRAL OXYGENATION DURING BOTTLE FEEDING IN PRETERM INFANTS: A NEAR-INFRARED SPECTROSCOPY STUDY (NIRS). Pediatr Res 32, 612 (1992). https://doi.org/10.1203/00006450-199211000-00043
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DOI: https://doi.org/10.1203/00006450-199211000-00043