Abstract
The purpose of the present study was to investigate the serum levels of the three vitamin D metabolites (25OHD, 24,25(OH)2D and 1,25(OH)2D) and osteocalcin in children aged 11-18 years during the summer and winter months. Two groups of twenty children each, were studied. The results are shown on the table:
*p<0.05. The comparison has been made between the two groups.
Our findings demonstrate that the levels of 25OHD and 24,25(OH)2O are higher in the summer than in winter(p<0.05) and are consistent with previous reports. In 4/10 children aged 10-18 yrs, 25OHD levels were found to be reduced significantly during the winter months(<10ng/ml). Similar seasonal variations were observed in the levels of 1,25(OH)2D (p<0.05), which was more pronounced in the older children (>11yrs). Although the osteocalcin concentrations were in general lower during winter, these findings were not statistically significant. Whether supplementation of vit.D during the winter months would have a beneficial effect on the growth of the older children (11-18yrs) is a matter that is presently under investigation.
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Lapatsanis, D., Chall, A. & Papadopoulou, Z. 160 VITAMIN D METABOLITE LEVELS IN CHILDREN. Pediatr Res 30, 654 (1991). https://doi.org/10.1203/00006450-199112000-00190
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DOI: https://doi.org/10.1203/00006450-199112000-00190