Abstract
We have previously reported the prediction of neurodevelopmental outcome at 4 years from the results of neurodevelopmental assessment at one year in a cohort of very preterm (<33 weeks) infants (1). At one year infants were classified by ihe presence of neurological impairment (major, with disability; minor, without disability) and the results of developmental testing (DQ). To investigate prediction ai 8 years, 95% of the cohort were re-examined at a mean age of 98 (SD ±4) months with clinical and neurological examinations, tests of hearing, vision, visuo-motor integration (Beery), cognitive functioning (WISC-R, K-ABC) and school achievement (K-ABC). The main results were:
Multiple regression analysis showed that neurological impairment at one year was a highly significant independent predictor of outcome at 8 years (p<0.001) whereas DQ at one year was not.
1. Stewart el al., Dev Med Child Neurol. 1988;30:53-63
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Roth, S., Baudin, J., Townsend, J. et al. 49 NEUROLOGICAL IMPAIRMENT AT ONE YEAR PREDICTS NEUROLOGICAL AND COGNITIVE OUTCOME AT EIGHT YEARS IN VERY PRETERM INFANTS. Pediatr Res 30, 636 (1991). https://doi.org/10.1203/00006450-199112000-00079
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DOI: https://doi.org/10.1203/00006450-199112000-00079
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