Abstract
We have previously reported the prediction of neurodevelopmental outcome at one and 4 years from neonatal ultrasound brain scan findings in a cohort of very preterm (<33 weeks) infants (1). To investigate prediction of outcome at school age 95% of the cohort were re-examined at a mean age of 98 (SD ±4) months with clinical and neurological examinations, tests of hearing, vision, visuo-motor integration (Beery), cognitive functioning (WISC-R, K-ABC) and school achievement (K-ABC). The mam results were:
Multiple regression analysis confirmed: 1. Hydrocephalus/cerebral atrophy and ventricular dilalation were highly significant independent predictors of neurodevelopmental impairment, IQ and school performance at 8 years in very preterm infants (p<0.001) 2. Neither uncomplicated PVH nor normal scans were significant predictors of outcome at 8.
1. Costello et al., Dev Med Child Neurol 1988:30:711-722.
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Baudin, J., Roth, S., Townsend, J. et al. 48 NEONATAL ULTRASOUND BRAIN SCAN FINDINGS PREDICT NEUROLOGICAL AND COGNITIVE OUTCOME AT EIGHT YEARS IN VERY PRETERN INFANTS. Pediatr Res 30, 636 (1991). https://doi.org/10.1203/00006450-199112000-00078
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DOI: https://doi.org/10.1203/00006450-199112000-00078